Tiny Conspiracies: Cell-to-Cell Communication in Bacteria

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Air date:	Wednesday, March 10, 2004, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 100 * This only includes stats from October 2011 and forward.
Category:	WALS - Wednesday Afternoon Lectures
Runtime:	01:05:00
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Description:	Quorum sensing, or the control of gene expression in response to cell density, is used by bacteria to regulate a variety of physiological functions. Quorum sensing bacteria produce, release and detect extracellular signalling molecules called autoinducers that accumulate in the environment as the cell population increases. In the bioluminescent marine bacterium V. harveyi, two parallel quorum sensing systems exist and function to control light production. System 1 is composed of Sensor 1 and Autoinducer-1 (AI-1), and System 2 is composed of Sensor 2 and Autoinducer-2 (AI-2). Our results suggest that V. harveyi uses AI-1 for intra-species communication and AI-2 for inter-species cell-cell signalling. The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

Author:	Bonnie Bassler, Ph.D., Princeton University
Rights:	This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
CIT Live ID:	2617
Permanent link:	https://videocast.nih.gov/watch=2617

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