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Douglas Laufenberger
It is becoming increasingly appreciated that to more fully understand how cells function as integrated biochemical and biophysical molecular systems, an intimate combination of quantitative experiment and computational modeling is required.
Garrett Odell
George von Dassow, Eli Meir, Ed Munro, and I made mathematical models of two genetic networks operating in early Drosophila embryos - the segment polarity network and the neurogenic network. Published experimental results fixed the topology of interactions between gene products.
Lucille Shapiro
With the goal of modeling the complete genetic circuitry of a bacterial cell, we are currently focused on defining the genetic network that coordinates cell differentiation as a function of the Caulobcter cell cycle.
Author:
Douglas Laufenberger, Garrett Odell and Lucille Shapiro
Runtime:
02:03:26
Rights:
This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.