NIH VideoCast - Fattening Up T Cell Memory

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Fattening Up T Cell Memory

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Air date:	Wednesday, June 17, 2015, 4:15:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 618 (56 Live, 562 On-demand)
Category:	Immunology
Runtime:	01:00:02
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Immunology Interest Group Dr. Susan Kaech is Associate Professor of Immunobiology and HHMI Early Career Scientist at Yale University. After receiving her Ph.D. from Stanford University for her studies in the field of developmental biology, Dr. Kaech joined the laboratory of Dr. Rafi Ahmed for her postdoctoral training. During this period, she made seminal discoveries in the area of effector and memory T cell development. In particular, she provided the first molecular and functional profiling of effector and memory CD8+ T cells and identified cellular precursors of long-lived memory CD8+ T cells. She became assistant professor at Yale University in 2004, and was promoted to associate professor in 2009. Her work as independent investigator has profoundly shaped our current understanding of how CD8+ memory T cells are formed. She elucidated key transcriptional regulators that control CD8+ T cell differentiation, such as T-bet, Blimp-1, and STAT3, and she has also identified pivotal cytokines that regulate effector and memory cell fate decisions, including IL-12, IL-10 and IL-21. Dr. Kaech has been a recipient of numerous awards including the Burroughs-Wellcome Foundation Award in Biomedical Science (2003), the Cancer Research Institute Investigator Award (2005), and the Presidential Early Career Award for Scientists & Engineers, NIH (2007). For more information go to http://sigs.nih.gov/immunology/Pages/default.aspx

NLM Title:	Fattening up T cell memory / Susan Kaech.
Author:	Kaech, Susan. National Institutes of Health (U.S.). Immunology Interest Group,
Publisher:
Abstract:	(CIT): Immunology Interest Group Dr. Susan Kaech is Associate Professor of Immunobiology and HHMI Early Career Scientist at Yale University. After receiving her Ph.D. from Stanford University for her studies in the field of developmental biology, Dr. Kaech joined the laboratory of Dr. Rafi Ahmed for her postdoctoral training. During this period, she made seminal discoveries in the area of effector and memory T cell development. In particular, she provided the first molecular and functional profiling of effector and memory CD8+ T cells and identified cellular precursors of long-lived memory CD8+ T cells. She became assistant professor at Yale University in 2004, and was promoted to associate professor in 2009. Her work as independent investigator has profoundly shaped our current understanding of how CD8+ memory T cells are formed. She elucidated key transcriptional regulators that control CD8+ T cell differentiation, such as T-bet, Blimp-1, and STAT3, and she has also identified pivotal cytokines that regulate effector and memory cell fate decisions, including IL-12, IL-10 and IL-21. Dr. Kaech has been a recipient of numerous awards including the Burroughs-Wellcome Foundation Award in Biomedical Science (2003), the Cancer Research Institute Investigator Award (2005), and the Presidential Early Career Award for Scientists & Engineers, NIH (2007).
Subjects:	T-Lymphocytes--immunology
Publication Types:	Lecture Webcast

NLM Classification:	QW 568
NLM ID:	101663002
CIT Live ID:	16506
Permanent link:	https://videocast.nih.gov/watch=16506

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