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Max Wicha is the founding Director of the University of Michigan Comprehensive Cancer Center. He also serves as the Distinguished Professor of Oncology, Professor of Internal Medicine and is nationally known for his research in the field of cancer stem cells. His laboratory was part of the team that first identified breast cancer stem cells, the first such cells identified in solid tumors. His laboratory identified a number of stem cell markers and developed in vitro and mouse models to isolate and characterize these cells, models which have been widely utilized in the field.
LECTURE OBJECTIVES: 1) to understand the role of stem cells in breast carcinogenesis; 2) to gain knowledge of the pathways that isolate normal and malignant stem cells; and 3) to understand how these stem cell regulating pathways may be regulated by dietary components, including curcumin and sulforaphane.
Chemoprevention using natural dietary components to target cancer stem cells [electronic resource] / Max S. Wicha.
Series:
Targeting mammary stem cells for breast cancer prevention
Author:
Wicha, Max S. National Institutes of Health (U.S.)
Publisher:
[Bethesda, Md. : National Institutes of Health, 2011]
Other Title(s):
Targeting mammary stem cells for breast cancer prevention
Abstract:
(CIT): Stars in Nutrition and Cancer Max Wicha is the founding Director of the University of Michigan Comprehensive Cancer Center. He also serves as the Distinguished Professor of Oncology, Professor of Internal Medicine and is nationally known for his research in the field of cancer stem cells. His laboratory was part of the team that first identified breast cancer stem cells, the first such cells identified in solid tumors. His laboratory identified a number of stem cell markers and developed in vitro and mouse models to isolate and characterize these cells, models which have been widely utilized in the field. LECTURE OBJECTIVES: 1) to understand the role of stem cells in breast carcinogenesis; 2) to gain knowledge of the pathways that isolate normal and malignant stem cells; and 3) to understand how these stem cell regulating pathways may be regulated by dietary components, including curcumin and sulforaphane.
Subjects:
Breast Neoplasms--prevention & control Curcumin--therapeutic use Neoplastic Stem Cells Nutrition Therapy Thiocyanates--therapeutic use
