NIH VideoCast - Cerebellar Learning: Beyond the Purkinje Cell

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Cerebellar Learning: Beyond the Purkinje Cell

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Air date:	Monday, October 31, 2011, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 454 (21 Live, 433 On-demand)
Category:	Neuroscience
Runtime:	01:08:20
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Neuroscience Seminar Series Dr. Sascha du Lac's research is focused on the neural mechanisms of learning. They use motor learning in eye movements as a model system to examine how cellular and molecular mechanisms of plasticity operate in the context of neural circuits to improve behavioral performance. Their laboratory employs a variety of techniques to identify mechanisms by which the cerebellum controls motor learning, including behavioral analyses of eye movements in transgenic mice and cellular physiological studies in brain slices. They study learning in a well-defined behavior, the vestibulo-ocular reflex (VOR), which enables clear vision during head movements. Learning in the VOR occurs whenever vision is compromised persistently during head movements. The neural circuitry for the VOR is well understood, enabling us to link specific cellular and molecular mechanisms with their consequences for learning. Their lab studies how changes in intrinsic neuronal excitability and synaptic transmission operate within the circuit for the VOR to transform experience into adaptive changes in behavior.

NLM Title:	Cerebellar learning : beyond the Purkinje cell / Sascha du Lac.
Author:	Du Lac, Sascha. National Institutes of Health (U.S.)
Publisher:
Abstract:	(CIT): Dr. Sascha du Lac's research is focused on the neural mechanisms of learning. They use motor learning in eye movements as a model system to examine how cellular and molecular mechanisms of plasticity operate in the context of neural circuits to improve behavioral performance. Their laboratory employs a variety of techniques to identify mechanisms by which the cerebellum controls motor learning, including behavioral analyses of eye movements in transgenic mice and cellular physiological studies in brain slices. They study learning in a well-defined behavior, the vestibulo-ocular reflex (VOR), which enables clear vision during head movements. Learning in the VOR occurs whenever vision is compromised persistently during head movements. The neural circuitry for the VOR is well understood, enabling us to link specific cellular and molecular mechanisms with their consequences for learning. Their lab studies how changes in intrinsic neuronal excitability and synaptic transmission operate within the circuit for the VOR to transform experience into adaptive changes in behavior.
Subjects:	Cerebellum--physiology Learning--physiology Memory--physiology Neuronal Plasticity--physiology Neurons--physiology Purkinje Cells--physiology
Publication Types:	Lecture Webcast

NLM Classification:	WL 320
NLM ID:	101574465
CIT Live ID:	10637
Permanent link:	https://videocast.nih.gov/watch=10637

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