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This presentation was given as part of the annual training course, Institute on Systems Science and Health (ISSH), produced by the Office of Behavioral and Social Sciences Research at the National Institutes of Health with support from the Center for Disease Control and Prevention. The objective of ISSH is to provide attendees with a thorough introduction to selected systems science methodologies in one of three tracks: agent based modeling, system dynamics modeling, and network analysis. The videocasts of the ISSH plenary sessions are made available on this website. To apply for a future ISSH contact Patty Mabry at: mabryp@od.nih.gov