I'M THE FIRST TO WELCOME YOU I'M

BETSY HUMPHREYS, I'M THE DEPUTY

DIRECTOR OF THE NLM.

MY FIRST DUTY IS TO INTRODUCE

THE DIRECTOR OF THE NATIONAL

LIBRARY OF MEDICINE WHO ACTUALLY

HAS BEEN RESPONSIBLE FOR THE

DEVELOPMENT OF QUITE A FEW COOL

APPS HIMSELF, BOTH BEFORE AND

AFTER HE CAME TO THE NATIONAL

LIBRARY OF MEDICINE SO I WILL

TURN IT OVER TO DR. DONALD

LINDBERG.

[ APPLAUSE ]

>> WELL, FOLKS, GOOD MORNING AND

WELCOME.

HAPPY DAY.

GLAD TO BE HERE.

ACTUALLY I'M GOING TO DODGE A

BULLET BY TAKE THANKSGIVING

OPPORTUNITY TO INTRODUCE

SECRETARY SEBELIUS WHO HAS BEEN

KIND ENOUGH TO GIVE US A

RECORDED TV AND SO SHE'LL COME

ON.

IT'S A MAGIC ROOM, SO I DON'T

KNOW HOW IT WILL HAPPEN BUT IT

WILL HAPPEN.

AND THEN I'LL GET BACK TO YOU.

>> HI, I'M SECRETARY OF HEALTH

AND HUMAN SERVICES KATHLEEN

SEBELIUS AND I WANT TO WELCOME

YOU TO THE AWARDS CEREMONY FOR

THE NATIONAL LIBRARY OF

MEDICINE'S FIRST EVER SOFTWARE

DEVELOPMENT CHALLENGE IT IS,

IT'S PART OF THE YEAR LONG

150th CELEBRATION.

ON BEHALF OF THE ENTIRE

DEPARTMENT, I WANT TO

CONGRATULATE DONALD LIND BERG

AND EVERYONE AT THE NATIONAL

LIBRARY OF MEDICINE IN THIS

AMAZING MILESTONE.

THE FOUNDERS OF OF THE LIBRARY

RECOGNIZE THE POWER OF PUBLIC

INFORMATION TO IMPROVE THE LIVES

OF THEIR FRIENDS AND NEIGHBORS

AND ALSO THE LIVES OF

GENERATIONS TO COME BUT I THINK

THEY'D BE AMAZED TODAY TO SEE

HOW FAR YOU HAVE COME.

THE LIBRARY STANDS OUT NOT JUST

IN AMERICA BUT AROUND THE WORLD

AS THE MOST TRUSTED RESOURCE FOR

MEDICAL INFORMATION.

EVERYDAY MILLIONS OF PEOPLE

ACCESS THE LIBRARIES DATABASES

TO SEARCH EVERYTHING FROM

HISTORICAL IMAGES TO DNA

SEQUENCES.

BUT IT DOESN'T STOP THERE, YOU

AT THE LIBRARY ARE CONSTANTLY

DEVELOPING NEW AND INNOVATIVE

WAYS TO MAKE INFORMATION

AVAILABLE SO THAT IT CAN BE USED

TO IMPROVE PUBLIC HEALTH.

THE CHALLENGE COMPETITION IS

JUST THE LATEST EXAMPLE OF THE

LIBRARY EMBRACING NEW WAYS TO

PUT ITS DATA TO THE BEST USE.

I WANT TO CONGRATULATE ALL THE

APPLICANTS, ESPECIALLY TODAY'S

WINNERS AND URGE ALL OF YOU TO

KEEP INNOVATING.

AS THE SECRETARY OF HEALTH AND

HUMAN SERVICES I'VE HAD THE

PLEASURE OF SEEING SOME OF THE

LIBRARIES WONDERFUL PROJECT AND

ADVANCES FIRST HAND AND MEETING

THE STAFF WHO DEVELOP THEM AND I

REMAIN COMMITTED TO MAKING THE

DEPARTMENT'S DATA RESOURCES

READILY AVAILABLE TO SPUR

INNOVATION.

IN FACT, WE'RE USING YOUR WORK

AS A MODEL FOR NEW EFFORTS LIKE

OUR DEPARTMENT WIDE HEALTH DATA

INITIATIVE.

EACH OF OUR AGENCIES NOW UPDATES

ME TWICE A YEAR ON HOW THEY'RE

MAKING THEIR DATA MORE

ACCESSIBLE.

SO ON THIS SPECIAL DAY, I WANT

TO THANK ALL OF YOU WHOSE HARD

WORK AND DEDICATION HAVE BEEN A

PART OF THE NATIONAL LIBRARY OF

MEDICINE STORY AND I WANT TO

CHALLENGE ALL OF US TO DO OUR

PART TO MAKE THE NEXT 175 YEARS

AS SUCCESSFUL AS THE FIRST.

[ APPLAUSE ]

>> WELL, I'M GRATEFUL FOR

SECRETARY FOR JOINING US BY

VIDEO AND I WOULD ALSO LIKE TO

THANK THOSE FOR TAKING THE

TROUBLE TO COME OUT AND BE WITH

US.

A BRIEF HISTORY MOMENT, MORE

THAN 40 YEARS AGO, NLM STARTED

SHARING THESE DATABASES, BUT

THAT THE TAPES COULD BE

RELOCATED WHICH INENTIALLY WAS

IN ENGLAND AND THEN IN FRANCE BY

THE MODE OF EITHER TRANSMISSION

OR SATELLITES OR JUST READING

TAPES AND OF COURSE, IN THOSE

DAYS, THIS WAS IN THE 60S, IF

ENGLAND DECIDED TO DO TAPE AND

FRANCE DECIDED TO DO ELECTRONIC

AND VICE VERSA, BUT LIFE WAS

ALWAYS THAT WAY.

I CAME IN '84 AND MARY AND I

SHORTLY WENT TO BEIJING, CHIN

ABIGGEST COUNT--CHINA, BIGGEST

COUNTRY IN THE WORLD BUT WE DID

INSTALL WITH THE HELP OF NLM A

TAPE SYSTEM WITH DIFFICULTY BUT

EACH THAT COULD ONLY SERVE FOR

THEIR LUCKY BEIJING.

THAT'S A HUGE PLACE.

SO I DECIDED THAT'S THE LAST

TAPE THING WE'RE GOING TO PUT

IN.

TOO MUCH DIFFICULTY.

AFTER THAT WE'RE GOING

ELECTRONIC OFF THE SATELLITES

AND WE WENT TO ISRAEL.

AGAIN, A NUMBER OF PEOPLE FROM

NLM ALONG WITH ME.

AND THE ISRAELIS SAID WAIT A

MINUTE, DON'T YOU UNDERSTAND

IT'S VERY, VERY, DIFFICULT TO DO

THIS ELECTRONICALLY OFF

SATELLITES, I SAID SURE THAT'S

WHY I CAME, I WANT SMART

COLLABORATORS I CAME TO ISRAEL.

WELL, YOU KNOW, OKAY.

SO THEY ROSE TO THE CHALLENGE

AND DID A GOOD JOB.

SO THERE'S A LITTLE PROGRESSION

HERE BUT WE HOP UP TO 2011, WE

HAD A MEETING IN SEPTEMBER WITH

IBM WATSON GROUP WHO OF COURSE

HAD WON THE CONTEST, THE

JEOPARDY CONTEST WHICH SOME OF

MY COLLEAGUES THINK IS A STUNT,

IT'S A LANDMARK OF ARTIFICIAL

INTELLIGENCE WORK, IT'S A MAJOR

ACCOMPLISHMENT AND THEY SPENT A

DAY WITH US, DAVID AND DAVID

GONDECH, AND THE REST OF THE

MANAGEMENT CREW AND WE DECIDED

AS OF YESTERDAY, YES WE'RE GOING

TO DO A JOINT PROJECT TOGETHER,

SO FOR ME, THE TOP PROJECT IS

NOT SECOND GUESSING DOCTORS AND

DIAGNOSIS, I MEAN I PLAYED THAT

GAME FOR 45 YEARS, WHAT WE WANT

TO DO IS DEVISE A SYSTEM CHAI

WILL HELP QUESTIONS THAT ARE

BROUGHT BY PATIENTS, FAMILIES

AND THE PUBLIC.

YOU MIGHT HAVE NOTED THERE'S

MORE PUBLIC THAN DOCTORS TO

BEGIN WITH AND IT'S AN

INTERESTING TASK AND IBM AGREED

WITH THAT AND WE'RE GOING TO

START IT.

INCIDENTALLY BETSY AND I WERE AT

PAINS TO MAKE SURE THAT IBM LEFT

FULLY IMPRESSED BY NLM SO WE HAD

A FULL STRING OF THINGS THAT

BEFORE WE GOT INTO THE RESEARCH

PROJECT BUT WE'RE UPSTAGED BY

DR. GANDACH, WHOSE OPENING

REMARKS WERE ALREADY A LICENSED

MLS USER AND HERE'S WHAT--AND

THAT'S HOW WE STARTED IT ALL.

OUR HEALTH COMPONENT IS THE MLS,

SO WE'RE SAVVY AND PROUD AND WE

COULD GET ON TO BUSINESS.

SO WHERE ARE WE NOW.

LOOK AT PROGRESSION.

WE'RE TALKING ABOUT INITIALLY

NATIONS MAKING A COMMITMENT TO

USE THESE SERVICES.

ENGLAND AND FRANCE COMPETING OF

COURSE, CHINA, A BIG DEAL,

ISRAEL, YOU KNOW THE HIGH TECH,

IBM PRETTY DARN BIG COMPANY AND

WHERE ARE WE NOW, WE'RE AT THE

CONTRIBUTION OF INDIVIDUALS, HOW

MUCH THE WORLD HAS CHANGED.

NOW THE WINNERS ARE NOT AS THE

JAPANESE SAY, THERE IS NO

ORDINARY CITIZEN, WHAT YOU HAVE

BEFORE YOU IS EDUCATED, SMART,

HARD WORKING AND IMAGINE NATIVE

PEOPLE, OF COURSE, THAT'S TOO

BIG A THING TO PUT ON A WATCH SO

YOU JUST HAVE TO SAY CITIZEN.

BUT, TO ME, IT'S AN INCREDIBLE

ADVANCE THAT THESE WONDERFULA

APPLICATIONS ARE NOT THE RESULT

OF HUNDREDS AND HUNDREDS OF

PROGRAMMING STAFF AND A MAJOR

CORPORATION OR A MAJOR NATION.

THEY'RE YOUR WONDERFUL PEOPLE.

SO I'M REALLY DELIGHTED YOU'RE

HERE AND I'M VERY PROUD OF AND

YOU I'M VERY, VERY, HAPPY THAT

WE HAVE SOME DOWN TIME VISITORS

TO COME AND CONGRATULATE YOU AS

WELL.

THANK YOU.

[ APPLAUSE ]

>> AND WE ARE VERY LUCK TOW HAVE

THE DEPUTY DIRECTOR OF THE

NATIONAL INTUITYS OF HEALTH,

DR. LARRY TABAK TO HELP US ENJOY

THIS WONDERFUL OCCASION.

THANK YOU, LARRY.

>> WELL, GOOD MORNING EVERYBODY

AND THANK YOU BETSY AND WELCOME

TO ANEESH ANDED TODD, GREAT FOR

YOU TO JOIN US THIS MORNING.

THIS IS A PREMIER DAY.

WHEN I FIRST READ THE--ON MY

BLACKBERRY, THE TITLE, SHOW OFF

YOUR--I THOUGHT IT WAS SHOW OFF

YOUR ABS.

[LAUGHTER]

I GOT REALLY NERVOUS SO FIRST

AND FOREMOST, I WANT TO

CONGRATULATE ALL OF THE

AWARDEES, THIS IS--THIS IS GREAT

AND IN FACT, I WANT TO

CONGRATULATE ALL THE PEOPLE WHO

EVEN ENTERED.

YOU KNOW THIS WAS AN INAUGURAL

COMPETITION AND THE CREATIVITY

THAT EACH OF YOU HAS

DEMONSTRATED REALLY IS--IT'S

INSPIRATIONAL AND I MUST SAY,

SOBERING FOR SOME OF OF US WHO

STILL THINK THEY'RE BACK IN THE

TAPE--TAPE ERA, SO ON BEHALF OF

NIH, LET ME THANK YOU FOR

SHARING A PORTION OF YOUR

INGENUITY WITH US AND PLEASE,

THIS SHOULDN'T BE THE END.

PLEASE CONTINUE TO DREAM UP

GREAT NEW WAYS OF NIH TO GET OUT

OUR HEALTH AND OUR SCIENCE

MESSAGES, TO THE PUBLIC AT

LARGE.

YOU KNOW INNOVATION IS THE KEY

TO WHAT NIH IS ALL ABOUT AND

WE'RE FIRMLY COMMITTED TO MAKING

DATA AND INFORMATION AVAILABLE.

IT'S REALLY PART OF A KEY

STRATEGY AND PROMOTING

INNOVATION AND TURNING DISCOVERY

INTO HEALTH.

NOW, AS YOU HAVE HEARD AND ALL

KNOW NLM IS JUST--IT'S JUST SO

VITAL IN THE MANY ROLES THAT IT

PLAYS IN ENABLING NIH TO SHARE

RESEARCH RESULTS AND HIGH

QUALITY HEALTH INFORMATION AND

THAT'S REALLY THE KEY IS TO BE

ABLE TO DISCRIMINATE FACT FROM

WHAT'S NOT SO FACTFUL.

THEIR SYSTEMS GET A MIND

BOGGLING AMOUNT OF USE.

LITERALLY BILLIONS OF SEARCHES A

YEAR.

YOU KNOW PEOPLE COME DIRECTLY TO

NLM WEB SITES, OR, AS I'VE NOW

LEARNED AND BETSY HAS BEEN GREAT

IN TUTORING ME, THEY RETRIEVE

INFORMATION FROM NLM WITHOUT

KNOWING IT WHEN THEY HIT GOOGLE.

WHO KNEW?

YOU KNOW BUT THERE IT IS.

AND SOW OF COURSE THEY ARE

INCEILINGINGLY

USING--INCREASINGLY USING APPs

TO DO THE SAME THING.

NOW WE ALL KNOW HOW QUICKLY

TECHNOLOGY MOVES AND CHANGES.

BY THE TIME I FIGURE OUT HOW TO

USE A GADGET IT'S P A SSE AND IT

DRIVES ME CRAZY AND BIOMEDICAL

RESEARCH DOESN'T MOVE QUITE AS

RAPIDLY AS TECHNOLOGY AND IN

MANY CASES IT'S MORE INCREMENTAL

IN SPEED BUT EVEN SO IT'S STILL

REALLY DIFFICULT TO KEEP UP

BECAUSE OF THE ENORMOUS AMOUNT

OF INFORMATION AND THAT'S WHY

THIS SORT OF EVENT AND YOUR

EFFORTS ARE SO VERY, VERY,

IMPORTANT.

SO MY MESSAGE TO ALL OF YOU

TODAY IS SIMPLY AND THIS WILL

SHOW MY AGE A BIT, IN THE WORDS

OF ICONIC ERO SMITH SONG--ARROW

SMITH SONG:  DREAM ON.

IT'S ABOUT 40 YEARS OLD NOW,

THAT SONG.

BUT I THINK THAT LYRIC IS MORE

VITAL TODAY THAN IT WAS BACK

WHEN IT WAS FIRST PENNED.

WE CAN'T AFFORD TO REST ON OUR

LAURELS, WE CAN'T EVERY SLOW OUR

MOMENTUM AND IT'S ABSOLUTELY

TRUE FOR INNOVATION AND

CREATIVITY.

SO LET'S CELEBRATE TODAY'S

GENIUS.

YOU DESERVE IT AND THANK YOU TO

NLM FOR COORDINATING THIS.

AND JUST IN CLOSING, I WANT TO

TAKE THE OPPORTUNITY TO ALSO

CONGRATULATE NLM ON THE 175th

ANNIVERSARY THIS YEAR AS THE

LARGEST MEDICAL LIBRARY IN THE

WORLD.

AND THE DEVELOPER OF SO MANY

INNOVATIVE ONLINE RESOURCES, NLM

PLAYS SUCH A VITAL ROLE IN NIH'S

MISSION TURNING DISCOVERY INTO

HEALTH.

SO, I WANT TO THANK EACH AND

EVERY ONE OF YOU FOR BEING HERE

TODAY AND CERTAINLY LOOK FORWARD

TO THE REST OF THE PROGRAM.

THANK YOU.

[ APPLAUSE ]

>> I HAVEN'T WATCHED THE ACADEMY

AWARDS IN QUITE A WHILE, BUT I

KNOW THAT IT USED TO BE THE

PRICE WATER HOUSE WOULD COME OUT

AND TELL YOU WHAT THE RULES

WERE.

SO I'M JUST GOING TO TELL YOU

WHAT THE RULES WERE FOR THIS, SO

THAT YOU--AND GIVE A THANK YOU

TO SOME OF THE MANY PEOPLE WHO

HELP MAKE THIS POSSIBLE.

IT'S EASY FOR ME TO BE INSPIRED

BY ANEESH AND TODD TO SAY LET'S

GIVE A CHALLENGE BUT IN FACT,

IT'S A LOT OF WORK TO PUT THIS

TOGETHER AND THIS WONDERFUL

COMMITTEE UNDER DIANE BASKEY,

HAS DONE AN AMAZING THING.

THOSE OF YOU WHO ARE NOT NLMERS

DO NOT NEED TO KNOW WHO THESE

MEAN.

BUT THEY DO HAVE EVERY PART OF

NLM TO CONTRIBUTE TO THIS AND

THEY DID A SPLENDID JOB.

SO IN GENERAL, THE ELIGIBLE

CRITERIA ARE LISTED HERE.

YOU HAD TO USE NLM DATA, YOU HAD

TO HAVE SOMETHING THAT WAS--USED

THE DATA IN A REASONABLE AND

HIGH QUALITY AND ACCURATE

METHOD.

YOU--WE WERE--YOU'RE BEING

EVALUATEDOT IMPACT ON POTENTIAL

USERS, USABILITY AND INNOVATIVE

DESIGN PLATFORM NEUTRALITY,

EXTENSIBILITY AND ALIGNMENT WITH

SECTION 508 REQUIREMENTS.

WE WERE THRILLED.

WE GOT 42 SUBMISSIONS, 25 OF--AS

YOU CAN SEE HERE, SPLIT BETWEEN

THOSE THAT WERE ESSENTIALLY WEB

BASED OR MOBILE OR BOTH.

WE ENDED UP WITH FIVE WINNERS

AND FIVE HONORABLE MENTIONS.

THERE WERE OVER 40 SEPARATE NLM

DATA SETS THAT WERE USED AND YOU

WOULDN'T BE SURPRISE THAD

MEDLINE AND PUB MED WAS USED THE

MOST BUT THERE REALLY WAS A LOT

OF DIFFERENT USE AND WHEN WE SAY

A HUNDRED OCCURRENCE OF DATA

SET, IT'S THAT MANY OF THESE

APPLICATIONS WERE USING MULTIPLE

MLM SERVICES AND PUTTING THEM

TOGETHER AND PUTTING THEM

TOGETHER WITH OTHER PEOPLE'S

DATA AS WELL WHICH IS GREAT.

WE HAD--WE RAN THE CONTEST FROM

APRIL THROUGH THE END OF AUGUST

AND THE REVIEW AND JUDGING TOOK

PLACE IN SEPTEMBER AND THEN WE

HAD OUR FIRST PRELIMINARY

ANNOUNCEMENT OF THE WINNERS A

WHILE AGO.

SO, BECAUSE OF THE THIS NOTION

OF WE WANTED TO BE SURE THAT

THERE WAS ACCURATE AND

REASONABLE USE EVER THE DATA, IT

REALLY TOOK AN ARMY OF PEOPLE TO

GO THROUGH VERY CAREFULLY TO BE

SURE THAT THESE APPLICATIONS

WERE DOING SOMETHING SENSIBLE

AND HADN'T SORT OF--TO USE AS A

SILLY EXAMPLE, MARRIED THIS

AUTHOR TO SOMEBODY ELSE'S TITLE

OF ARTICLE OR SOMETHING.

SO THIS WAS A BIG JOB AND THIS

CROWD, WE CAN'T THANK THEM

ENOUGH FOR DOING IT AND THEN WE

BROUGHT IN EXTERNAL JUDGES,

PEOPLE WHO SERVE AS MEMBERS OF

VERSE NLM ADVISORY COMMITTEES TO

BE THE FINAL DECIDERS AND THEY

HAD A VERY, VERY, HARD JOB.

EMPLOY SO THAT'S HOW THIS WAS

ALL PUT TOGETHER AND WE ARE

REALLY DELIGHT THAD WE HAVE

ANEESH CHOPRA WHO IS THE UNITED

STATES CHIEF TECHNOLOGY OFFICER

AND I WANT TO READ THIS TO BE

SURE I GET THE TITLE RIGHT AND

ALSOLET ASSOCIATE DIRECTOR--THE

ASSOCIATE DIRECTOR AT OSTP.

AND TODD PARK, THE HHS CHIEF

TECHNOLOGY OFFICER AND THEY HAVE

AGREED TO MAKE REMARKS AND ALSO

DO THE INTRODUCTIONS OF THE

WINNERS AND THE DEMONSTRATIONS.

I LEARNED THROUGH ALL OF THIS

THAT TODD PARK WAS BORN ON THE

SAME DAY THAT I CAME TO WORK FOR

THE NATIONAL LIBRARY OF MEDICINE

SO WE HAVE A COSMIC CONNECTION.

[CHEERING]

[ APPLAUSE ]

>> THANK YOU!

ALL RIGHT!

STAND WITH ME!

YOU KNOW, FOLKS, BETSY AND DON

SAID THANK US FOR COMING HERE

FROM WASHINGTON DOWN TOWN, IT'S

SORT OF IN REVERSE, WE WANT TO

SAY THANK YOU FOR YOUR

LEADERSHIP TO MAKE THIS HAPPEN

BECAUSE IT IS LEADERS LIKE YOU

THAT ARE ADVANCING THIS VERY

IMPORTANT NEW POLICY TOOL,

TAPPING INTO THE CREATIVITY AND

THE SPIRIT THAT HAS DRIP THE

AMERICAN STORY FOR GENERATIONS.

YOU'RE CARRYING IT TO THE NEXT

LEVEL, SO LET'S SAY THANK YOU TO

THE TWO OF THEM.

COME ON.

KD [ APPLAUSE ]

>> MAYBE I'LL SAY WHAT GOT US

STARTEDDED IN THIS AND YOU CAN

CARRY ON THE STORY.

BECAUSE THIS BEGANOT PRESIDENT'S

VERY FIRST DAY IN OFFICE WHEN HE

CREATED THE POSITION OF THE

CHIEF TECHNOLOGY OFFICER, THE

ROLE THEY SERVE, HIS

INSTRUCTIONS WERE THAT I WANT

OUR GOVERNMENT TO BE OPEN.

HE SPECIFICALLY SAID, I WANT

ECMENDATIONS ON HOW WE CAN BE

MORE TRANSPARENT, MORE

PARTICIPATORY AND MORE

COLLABRATIVE.

A VISION THAT HAS CARRIED HIM

HIS ENTIRE LIFE, AND WITH

TECHNOLOGY IT'S INCREDIBLY EASY

TO TAP INTO THESE POCKETS NO

MATTER WHERE THEY COME FROM, OR

WHERE THEY'RE IN THEIR

PROFESSIONAL LIVES OR AS WE

LEARNED EARLIER, NONE OF THEM

ARE NLM INVESTIGATORS.

TAPPING INTO THE NEW SOURCES OF

TALENT TO SOLVE THE SOURCES OF

THE DAY WAS HIS GOAL.

THIS SEPTEMBER, I HAD THE HONOR

AND PRIVILEGE OF JOINING THE

PRESIDENT ON THE SIDE LINES OF

THE UNITED NATIONS.

BIG HEAVY STUFF GOING ON UP

THERE.

HE GATHERED 40 HEADS OF STATE

AND TOGETHER THEY SIGNED AN

INTERNATIONAL OPEN GOVERNMENT

PARTNERSHIP AND A CHARTER,

PLEDGING TO ADOPT THE SAME

THEORY OF BOTTOM UP CHANGE IN

PARTS OF THE WORLD THAT YOU

NORMALLY DON'T ASSOCIATE WITH

AMERICAN DIPLOMATIC

COLLABORATION AND EIGHT OF THOSE

COUNTRIES INCLUDING THE U.S.

FORMALLY DEPLOYED THEIR OWN

NATIONAL ACTION PLAN TO

INSTITUTIONALIZE THE GREAT WORK

THAT YOU'RE SEEING EVEN HERE AT

THE NLM.

A MAGGOR THRUST OF THAT NATIONAL

ACTION PLAN, WAS TO ENCOURAGE

COMMUNITIES OF INNOVATORS COMING

TOGETHER WITH SUPPLIERS OF DATA.

LIKE OUR GOOD FRIENDS HERE AT

THE NLM, IN NEW COMMUNITIES OF

INTEREST, EMPHASIZING THE POWER

OF NEW PRODUCTS AND SERVICES AT

THE INTERSECTION OF THEIR

CREATIVITY AND THE ASSETS THAT

BELONG TO THE AMERICAN PEOPLE,

ASSETS LICK THE DATABASES HERE

AT NLM.

AND I WANT TO JUST SUGGEST ONE

FINAL OBSERVATION AND THEN I'LL

HAND IT OVER TO TODD TO SAY, HOW

IS BROTHER TODD MAKE

THANKSGIVING REAL AT HHS?

THE NOTION IS EXACTLY WHAT WE

SAW NOT JUST TODAY BUT

YESTERDAY, TODD AND I WERE WITH

THE VICE PRESIDENT, I SAT IN THE

WEST WING AS HE„i TALKED TO

COLLEGE PRESIDENTS THROUGHOUT

THE COUNTRY ON A VERY SENSITIVE

AND DIFFICULT SUBJECT, THE

CHALLENGES OF RIULENCE OF WOMEN

ON OUR COLEDGE CAMPS BUT HE TOO

EMBRACED THIS IRB SPIRIT OF

CHALLENGE AND 90 DAYS PRIOR

ISSUED A SIMILAR CALL TO ARMS TO

HELP WOMEN COMMUNICATE THEIR

DISSTRESS OR CONCERNS IN A

DISCLEAT WAY SO THEY CAN BE ONE

OR TWO CLICKS AWAY FROM HELP

WHEN THEY NEED IT MOST.

THE TEAMS THAT ONE THAT CONTEST

ARE LIKE WHAT WE HEAR TODAY,

TEAMS THAT CAME TOGETHER JUST

BECAUSE WE WERE CHALLENGED TO DO

SO.

HEY DO HAVE YOU A FREBD WHO CAN

HELP ME DO THIS.

LET'S DO THAT.

LET'S DO SOMETHING.

AN INSTANT TEAM IN 90 DAYS

PRODUCING AN APPLICATION THAT

WILL BE AVAILABLE FOR YOUNG

WOMEN ON COLLEGE CAMPUSES TO

HELP THEM STAY SAFE.

IT'S THE BOTTOM UP SPIRIT, THE

STORIES OF THESE ENTREPPE

PREENEURS THAT WILL BE THE REAL

HEROES OF THE DAY AND TOCK ABOUT

THE VIEWS OF IT, GIVE IT SOME

LOVE FOR TODD PARK.

>> THANK YOU.

IT'S WHAT HAPPENS TO BE HERE

TODAY.

>> SO MANY CONGRATULATIONS, A

TRUE NATIONAL TREASURE ON THE

AMAZING WORK NLM HAS BEEN DOING

AND ON THE CHALLENGE OF THE

WINNERS OF THE CHALLENGE, IT

COULD NOT BE MORE EXCITED ABOUT

WHAT YOU'RE DOING AS YOU HEARD

FROM THE SECRETARY, WE ARE

INCREDIBLE LIE PASSIONATE ABOUT

THE OPEN DATA AND INNOVATION TO

LITERALLY CHANGE THE WORLD,

SOMETHING MENTIONED THE HEALTH

DATA INITIATIVE.

SHE LAUNCH THD A YEAR AND HALF

AGO TO TURN HHS INTO THE NOAH OF

THE HEALTH DATA, NOAH, IS THE

NATIONAL ORCHIANIC AND

ADMINISTRATIVE--THEY'VE FUELED

PROGRAMS EVERYWHERE, THEY RAN A

SIMILAR PLAY IN THE 80S BY

LIBERATING GPS DATA WHICH

FUELING EVERYTHING FROM FOUR

SQUARE TO iPHONE AND

EVERYTHING IN BETWEEN.

>> FOUR YEARS AGO.

>> AND NLM HAS BEEN DOING OPEN

DATA SINCE BEFORE IT WAS COOL.

AND THE NOTION NOW IS FOR HHS TO

BASICALLY GET NLMIZED, GPS-IZED

AND GET ALL THE INCREDIBLE

RESOURCES ACROSS HHS, CMS, FDA,

CDC, SO ON AND SO FORTH AND TURN

IT INTO ACCESSIBLE MACHINE

READABLE DATA AND KNOWLEDGE THAT

CAN BE TURNED INTO ALL KINDS OF

INCREDIBLE PRODUCTS AND

APPLICATION SERVICES AND HELP

CONSUMERS, PATIENTS, DOCTORS,

HOSPITALS EMPLOYERS,

JOURNALISTS, RESEARCHERS AND

IMPROVE HEALTH AND HEALTHCARE AS

WE KNOW IT AND WITH THE SPEED

AND VELOCITY OF DETH AND POWER

AND NO 10 COULD POSSIBLY DO, THE

UNDER LYING PRINCIPLE IS

SOMETHING WE CALL JOY'S LAW.

IT'S NAMED AFTER BILL JOY, THE

CONFOUNDER EVER SUN MICROSYSTEMS

AND HE SAID NO MATTER WHO YOU

ARE, YOU HAVE TO REMEMBER THAT

MOST OF THE SMART PEOPLE IN THE

WORLD DON'T WORK FOR YOU.

AND THE WHOLE PRINCIPLE OF THE

HEALTH INITIATIVE, THE WHOLE

PRINCIPLE THAT POWERED NLMs

OPEN DATA FOR DECADES AND YOU

WANT TO CHANGE THE ROLE WITH THE

POWER OF DATA DON'T JUST HAVE

YOUR OWN SMART PEOPLE WORK ON

IT, HAVE ALL THE OTHER SMART

PEOPLE IN THE WORLD WHO CARE

DESPERATELY, TAKE THAT POWER OF

THE DAT AND TURN INTO MAGIC.

TURN IT INTO PROGRAM, INSIGHTS

THAT CAN CHANGE LIVES BY THE

MILLIONS OR EACH THE BILLIONS

AND THAT'S WHAT WE'RE SEEING

WITH THE HEALTH DATA INITIATIVE

AND THAT'S WHAT WE'VE BEEN

SEEING FOR A VERY LONG TIME WITH

NLM AND WE COULD NOT BE MOIRE

EXCITED TO CELEBRATE THE OPEN

DATA NLM AS THEY SHOW THE REST

OF HHS, HOW IT'S DONE, HOW TO

ROLE WITH OPEN DATA AND HOW THE

CHANNEL ENJOYS THE LAW FOR THE

AMERICAN PEOPLE AND I CAN'T

THINK OF A BETTER WAY TO

ILLUSTRATE THAT THAN TO

CELEBRATE THE WINNERS WE HAVE

HERE TODAY SO WITHOUT FURTHER

ADIEU, GET TO THE MAIN EVENT.

>> GET TO THE MAIN EVENT.

>> CELEBRATING THE WINNERS OF

THE NLM SHOW OFF YOUR APPs

CHALLENGE N. A MINUTE, THE FIVE

WINNERS WILL COME UP AND SHOW

OFF THEIR APPS, BUT WE WANTS TO

RECOGNIZE THE HONOR MENTIONS.

>> AS WE SHOULD.

>> BECAUSE THEY'RE SPECTACULAR,

IT MUST HAVE BEEN A DIFFICULT

TASK BY THE JUDGES TO

DIFFERENTIATE.

BUT THE BIOINFORM PLATFORM,

SUPERCOOL, WORK NOTHING THE

LOST, DOING COOL STUFF.

IT'S A WEB BASED 3D PLATFORM

MANY YEARS IN THE MAKING THAT

SIMPLIFYS THE UNDERSTANDING OF

ANATOMY AND DISEASE.

INTERACTIVEt( TOOLS FOR
EXPLORING,

DISSECTING AND SHARING CUSTOM

VIEWS COMBINEDDED WITH DETAILED

EXPLANATIONS AND DESCRIPTIONS,

DERIVE FRIDAY MEDLINE PLUS

CONNECT AND PROVIDES A NEW

VISUAL FORMAT FOR PATIENTS AND

CLINICIANS TO REALLY LEARN ABOUT

THE--LEARN ABOUT THE BODY,

AMAZING AMAZING APPLAUSE.

WE CAN GIVE THEM APPLAUD.

>> YEAH.

>> SO BIODIGITAL SYSTEMS, SOHO,

IN NEW YORK CITY.

COOLEST NEIGHBORHOOD POSSIBLE.

DAILY MED PLUS PROVIDES ONLINE

ACCESS TO PHARMA INFORMATION,

AND DERIVED FROM SEVERAL

DATABASES, COMPREHENSIVE SEARCH

ENGINES AND HEALTH PROFESSIONALS

DEVELOPED BY MEDICOS, HERE IN

BALTIMORE.

>> ABSOLUTELY.

>> WE'RE RIGHT DOWN THE STREET.

>> ABSOLUTELY.

>> IN THE GENERAL AREA.

>> IN THE GREATER D.

C.-BALTIMORE AREA.

>> DRUG DIARY IS AN iPHONE

APP, WHICH HELP THEM„i MAINTAIN

PRESCRIPTIONS AND DATA SET AND

USE THESE FROM MEDLINE +.

IT WAS DEVELOPED BY JEFF REIGNS,

FOUNDER EVER FLOOD LIGHT

SOFTWARE IN THE GREAT CITY OF

CHICAGO.

>> CONGRATULATIONS CAN.

[ APPLAUSE ]

>> MOLECULE SYSTEM AN iPHONE,

iPOD AND iPAD APP.

IT HAS TOUCH BASE, USES INFO

FROM PUB CHEM DID THEA BASES,

WORK OF BRAD LARSON, GENERAL

MANAGER OF SUN SET LAKE SOFTWARE

IN MADISON WISCONSIN.

>> ALL RIGHT.

>> AND THEN ORKOF, IS AN

ANDROGEN ROADWAY THAT IS

INDENDRITIC CELLED BY MEDICAL

RESEARCHERSERS AND THE WORK OF A

TEAM IN VIENNA.

>> [ APPLAUSE ]

CONGRATULATIONS.

>> ON TO THE MAIN EVENT.

>> ON TO THE MAIN EVENT.

>> WHO ARE THESE WINNERS?

>> WHO ARE THE WINNERS?

WE'LL INTRODUCE EACH WINNING

APP, PLEASE HOLD QUESTIONS UNTIL

THE END OF ALL FIVE

PRESENTATIONS AND WE'LL DO ONE

AFTER THE OTHER, AND OPEN IT UP

FOR Q&A.

GRAD FOR YOU.

>> GLAD FOR YOU.

THE.

>> GLADFOUR U, HELPS ANSWER

QUESTIONS LIKE WHICH GENES ARE

RELATED TO BREAST CANCER.

TO ANSWER QUESTIONS RESEARCHERS

IDENTIFY ARTICLES VIA PUB MED

AND CREATE GENE LISTS BASED ON

MANUEL ANALYSIS OF THE ARTICLES.

>> THAT SOUNDS LIKE A LOT OF

WORK.

>> A TON OF WORK.

>> TON OF OF WORK.

>> AND TIME CON150U78ING AND THE

SMARTEST PEOPLE--TIME CONSUMING

AND THE SMARTEST PEOPLE MAKE

MISTAKES AND YOU MAKE THESE LIST

AND IT'S DIFFICULT.

SO A TEAM WITH A DEPARTMENT OF

BIOMEDICAL INFORMATICSA THE

GREAT UNIVERSITY OF VANDERBILT,

CREATED A WAY TO AUTOMATE THIS

PROCESS.

>> OH MY LORD!

>> YES.

>> WOW.

>> EFFICIENCY.

>> LEVERAGING THE POWER OF

TECHNOLOGY, IT'S GRAD-FOUR-U.

>> GENE LIST AUTOMATICALLY

DERIVED FOR YOU AND IT'S FOR THE

NATIONAL CENTER FOR

BIOTECHNOLOGY INFORMATION,

DR. GEROM JOURQUIN, AND WE LOVE

YOU AND WE HAVEN'T FORGOTTEN

ABOUT WHAT'S IMPOSSIBLE.

THEY REGULARLY INVENT IT, HE WAS

HELPED AND BIOINFORMATICS SYSTEM

ENGINEER, DEXTER AND THEY ARE

HERE NOW AND SHALL WE SHOW THEM

THE APP.

>> COME ON UP!

[ APPLAUSE ]

>> THANK YOU FOR THAT INTRUSION

AND I'M BING ZHANG AND THIS IS

JEROME JOURQUIN, IT IS SUCH A

PLEASURE TO BE HERE AND BE ABLE

TO ACCEPT THIS AWARD.

FIRST I WOULD LIKE TO THANK

NLMR. MR ORGANIZE--NLM FOR

ORGANIZING THIS AWARDS CEREMON

SCHEMORE IMPORTANTLY FOR IT IS

AWARDS AND RESOURCES FOR WHICH

THIS IS BASED.

WE KNOW GENES PLAY AN IMPORTANT

ROLE IN HOW WE LOOK AND ACT,

THEY ARE ALSO RELATED TO DISEASE

RISK, INITIATION, PROGRESSION,

AND TREATMENT.

SO IT'S NATURE OF INCEPTIVES TO

ASK QUESTIONS.

FOR EXAMPLE, WHICH GENES INVOLVE

THE EMBRYONIC DEVELOPMENT AND

WHICH GENES ARE RELATED TO

BREAST CANCER AND IN ORDERED TO

ANSWER THIS QUESTIONS, IT

INVOLVES VERY--TIME CONSUMING

PROCESSES.

AND I HOPE EVERYONE AGREES THAT

THE PUB MED IS THE MOST

COMPREHENSIVE RESOURCE FOR THE

ANSWERS FOR THESE TYPES OF

QUESTIONS.

BUT INCENTIVES COME TO PUB MED

AND PERFORM A PUB MED AND

RETRIEVE THESE PUBLICATIONS,

RAISE THE PUBLICATIONS AND

GENERATE THESE AND INTERPRET THE

GENE BASED.

GLAD-FOUR UUSTABBEDS FOR GENES

ADMINISTRATEY DERIVED FOR YOU

AND MAKE THIS SIMPLE SIMPLE

ACCURATE AND FAST PROCESS.

SO IN ADDITION TO GENERATE A

LIST OF GENES IT ALSO USES THAT

STATISTICAL ANALYSIS TO

PRIORITIZE THE GENES AND TRY TO

MAKE CONNECTIONS AMONG IT IS

GENES.

WE HAVE A PRIMARY DEVELOPER

EVALUATION PROCESS THE

APPLICATION HERE AND HE WILL

GIVE YOU THE DEMO.

>> I WANT TO THANKFUL THAT WE'RE

ALL HERE ESPECIALLY SINCE AFTER

A MONTH STUDYING THIS WE WERE

BABDED FROM NCBI TO USE THEIR

RESOURCES SO WE CAME ALONG

WITH--ANYWAY, THIS IS--IT'S A

LONG STORY.

[LAUGHTER]

>> WE LEARNED ALL THE RULES THAT

NEED TO APPLY TO THE SOFTWARE

VENLT BUT THIS IS GLAD FOR YOU,

THIS IS THE USER WILL ACTUALLY

INTERFACE WITH THE REASON THAT

WE DEVELOPED AND THE ONE GOAL WE

HAD--SO WE'RE FOCUSED ON HOW TO

USE THE APPLICATION AND DON'T

NEED ANY MANUEL AND JUST DIVE IN

SO THE WAY IT LOOKS IS JUST A

SEARCH BOX WITH QUERY ON TOP OF

IT SO PEOPLE WILL BE FAMILIAR

WITH THAT WHETHER IT'S WITH THE

MED OR GOOGLE AND TYPE THE

REQUEST WE ALSO KIND OF HAD ALL

THE OPTIONS THAT PEOPLE CAN USE

BY DEFAULTING TO WHICHEVER

PEOPLE MOSTLY USE, HAVING SAID

THAT THEY HAVE THE ABILITY TO

JUST GO IN AND CHANGE HOW THE

SOFTWARE WILL DEVELOP WILL

BEHAVE FOR THEM AND SO THE WAY

YOU USE IT, YOU USE IT PER P53

WHICH IS INVOLVED IN ALL

PURPOSES AND THE WAY THE

SOFTWARE WORKS RIGHT NOW WE'RE

HITTING THE MED SERVER TO

EXTRACT THESE THAT ARE

CORRESPONDING TO THIS KEY WORD

SO WHEN WE HAVE THE CITATION, WE

USE THE RESOURCES FROM THE NLM

TO TRANSFORM THAT INTO A LIST OF

GENES AND STOP PRIORITIZING THEM

SO AS THE RESULTS YOU SEE OVER

HERE, YOU SEE RIGHT AWAY THAT

OBVIOUSLY SINCE WE QUERY THE

GENE, THIS GENE APPEARS FIRST SO

THAT'S GOOD BECAUSE THAT'S WHAT

WE MEANT.

HAVING SAID THAT YOU SEE RIGHT

AWAY THAT THE RANKING OF THOSE

DIFFERENT GENES ARE WELL KNOWN

TO BE ASSOCIATED IN FUNCTION TO

BE GP53, AND THE OTHER THING

THAT WE DID WAS TO MAKE SURE

THAT USER HAVE ACCESS TO THE

OTHER RESOURCES FROM THE NCBI,

SO EVERY GENE THAT WE GIVE IS

AMILLIOLY LINKED TO GO FOR ALL

THE INFORMATION THAT I CAN THINK

OF FOR THIS GENE.

THE SAME WAY, THE OTHER PAGE WE

HAVE ACTUALLY A LIST OF ALL THE

PUBLICATION AND MADE THIS GENE

TO THIS EXPRAINK WITH THAT AGAIN

PEOPLE ABLE TO JUST ONE CLICK TO

GO TO THE ARTICLE SO THEY CAN

MAKE THEIR OWN JUDGMENT OF WHY

THIS GENE IS IN THIS POSITION.

DSM.

ANOTHER THING WE LOOK AT--WE

LIKE TODAY, WHICH IS WHY WE

DEVELOPED IT, BUT WE'RE ABLE TO

MAKE THIS LIST OF GENE ABLE TO

BE DOWNLOADABLE FOR THE USER FOR

EXTRA ANALYST WHICHEVER WAY THEY

WANT TO DO IT, WE ALSO PREPARE

FUNCTIONAL ENRICHMENT WHICH IS

ANOTHER ONE OF OUR SOFTWARE SO

JUST BY CLICKING IT, AND WE'RE

GETTING AROUND A LITTLE BIT,

GLAD FOR YOU, JUST SEND THIS

LIST TO THE OTHER SOFTWARE AND

JUST ONE CLICK, YOU'RE LABEL TO

HAVE ACTUALLY THE FUNCTIONAL

ENRICHMENT OF WHAT THIS IS YOU

HAVE, ANOTHER THING WE JUST DID

WAS TO TAKE THIS LIST AND

ACTUALLY INPUT IT INTO A

PROTEIN-PROTEIN INTERACTION

NETWORK.

LET'S GET THE FUNCTION ON

ENRICHMENT HERE SO WE'RE HAVING

THE DENOME ONTOLOGY AND

RESOURCES, AND IT'S VERY USEFUL

AND JUST BY SAYING THIS LIST OF

PEOPLE PEOPLE MAY WONDER WHAT

TYPE OF OF PROCESS MIGHT KNOW

INTERESTING IN THAT AND GLAD FOR

YOU AND YOU ARE HAVING READ ALL

THE ENRICHED PATHWAY SO CELL

CYCLE AND RISK TO DNA DAMAGE AND

ALL OF THAT IS JUST BY ONE CLICK

AWAY.

NOW I'M GOING TO TRY AGAIN TO

GET THE PROTEIN-PROTEIN

DIRECTION TO WORK AND JUST TO

PROVE HERE SOMETIMES IT JUST

DOESN'T WORK BUT WHAT IT IS AND

I CAN SHOW YOU AN EXAMPLE JUST

MAKE A POP UP WINDOW AND

PROTEIN, PROTEIN IRPT ACTION,

DERIVED FROM THE LIST OF GENES

THAT GLAD FOR YOU DID AND THAT'S

THE IRPT ACTIVE BECAUSE THIS IS

A PICTURE BUT YOU CAN ACTUALLY

MOVE AROUND AND HAVE AN IDEA

WHICH PROTEINS ARE KNOWN TO

INTERACT WITH ALL THE GENES THAT

YOU ACTUALLY EXTRACTED FROM YOUR

QUERY.

SO THIS IS GLAD FOR YOU, WE HAVE

MORE OUTSIDE, WE THANK YOU ALL

FOR BEING HERE AGAIN AND THANK

YOU FOR THE LIBRARY, VERY HAVING

US HERE.

[ APPLAUSE ]

>> YOU NOTICE THAT EMBRACE THE

SPIRIT OF OPENNESS BY ALLOWING

YOU TO TAKE YOUR DATA WITH YOU

WHEN YOU'RE DONE WITH YOUR

RESEARCH AND CLEARLY YOU

IMPROVED THE RESEARCHER IN THIS

SPACE SO THANK YOU.

>> IT WILL HAVE HUGE IMPACT.

THANK YOU SO MUCH.

>> THE SECOND WINNER WE'RE GOING

TO BRING UP IS iANATOMY,

ANYONE STUDYING ANATOMY CAN TAKE

ADVANTAGE OF THE NEXT WINNING

APP, THE ATLAS AVAILABLE FOR

THE iPHONE AND iPOD TOUCH,

THEY CAN USE INTERACTIVELY IN

USING THIS APP IN COOL WAYS.

DR. ANOUK STEIN.

IT'S HER FIRST iPHONE AND

IPAD APP.

SHE'S BUILT EIGHT MORE.

WHICH IS UNBELIEVABLE.

SHE'S USED DATA FROM NLM'S

VISIBLE HUMAN PROG EXPECT SHE

WILL DEMONSTRATE THE SUPER COOL

APP FOR US.

WELCOME ANOUK.

[ APPLAUSE ]

>> AYE, I'M ANOUK, STEIN, I'M A

COMPUTER PROGRAM AND AANALYST.

THANK TOUT NLM, AND OUR

SPEAKERS.

IMAGINE YOUR A BUSY MED STUDENT,

MED STUDENT OR PHYSICAL

THERAPIES, YOU DON'T HAVE MANY

AMOUNTS OF TIME BUT YOU HAVE TWO

OR THREE MINUTES AT A TIME

THROUGHOUT THE DAY.

I WILL SHOW YOU HOW TO USE THOSE

TO ACHIEVE REAL LEARNING.

iANATOMY IS A PORTABLE CROSS

SECTIONAL INTERACTIVE ANATOMY

ATLAS, YOU TOUCH THE STRUCTURE

AND THE APP DESIGNED THE NAME.

I DESIGNED AND PROGRAM THD

APP BY MYSELF.

THE FACE AND NECK IMPAGES AND

THE PELVIC IMAGES ARE FROM DATA

OF NLM'S VISIBLE HUMAN PROJECT

AND YOU CAN SEE THE ICON ON THE

FRONT MENU, IT CREATED

CRYOSECTION CT AND MR IMAGES OF

REPRESENTATIVE MALE AND FEMALE

CADAVERRERS AND LET ME GIVE YOU

A DEMONSTRATION.

OT FIRST SECONDS, YOU SEE BODY

SELECTIONS FROM THE FACE AND

NECK TO THE PELVIS, SO WE PICK

THE FACE AND NECK.

SO YOU TOUCH THE STRUCTURE AND

THE APP TELLS YOU THE NAME.

SO IF WE TOUCH NUMBER THREE, IT

TELLS US THAT'S THE MEDIAL

RECTIFIEDUS, SO WE SEE HERE

THESE ARE THE EYES AND NOSE,

THIS IS THE FRONT, THE BACK,

PATIENT RIGHT AND PATIENT LEFT.

AND WE'RE LOOKING AT THE PATIENT

AS IF WE'RE STANDING AT THEIR

FEET, LOOKING UP TO THEIR HEADS

SO AGAIN IT'S PATIENT RIGHT,

PATIENT LEFT.

ALONG THE BOTTOM ARE FOUR TABS,

MUSCLE, BONE, ORGANS AND BLOOD.

THE LABELS ARE SEGMENTED INTO

THESE FOUR CATEGORIES IN ORDER

TO LIM THE NUMBER OF LABEL O

SINGLE ANY ONE IMAGE AND TO

ACHIEVE FOCUS LEARNING.

SO THE USER FIRST SELECTS THE

BODY SECTION AND THEN WHICH

CATEGORY THEY WANT TO STUDY.

SO IF WE LOOK AT THE BONE, WE

CAN SEE, HERE'S THE MEDIAL

ORBITAL WALL, THE LATERAL

ORBITAL WALL.

HERE'S THE NASAL BONE AND FOR

THE ORGANS, THE DETAIL IS JUST

EXQUISITE ON THE CRYOSECTION.

SO THAT'S THE OPTIC NERVE.

YOU CAN ZOOM IN WITH THE DOUBLE

TAP AND WE THE LENS OF THE EYE,

HERE'S A PORTION OF THE BRAIN.

AND THERE'S THE INTERNAL CAROTID

ARTERY NOW THE APP IS FREE

STANDING AFTER THE INITIAL

DOWNLOAD, NO FURTHER INTERNET IS

REQUIREDDED THIS PAIKS IT

PERFECT IN USE FOR HOSPITALS

WHERE CONNECTIVITY CAN BE A

PROBLEM AND LEARN O GBA PUBLIC

TRANSPORTATION WHEN YOUR OTHER

APPs MAY BECOME USELESS.

NOW THE APP IS DESIGNED TO BE

MINIMAL AND SIMPLE.

MOST USERS'RE ONLY GOING TO USE

AN APP FOR LESS THAN TWO MINUTES

SO IT NEEDS TO BE MANAGEABLE AND

DIGESTIBLE WITHIN THAT TIME.

IT DISCREET FOCUS PACKETS SO YOU

CAN LEARN ABOUT MUSCLES OF THE

FACE ONE DAY, THE ORGANIZE--NLM

ANS OF THE PELVIS ANOTHER OR

MAYBE THE BLOOD VESSELS OF THE

ABNORMALITIES DOMIN ON ANOTHER.

THAT'S ALSO MEANT AS A REFERENCE

ATLAS.

SO IF WE GO TO SOME OF THESE

IMAGES, HERE IS THE NASAL ACCEPT

TUM, THE MAXILLARY SINUS; HERE

WE CAN SEE THE HARD PALLET, THIS

IS THE P A ROTID THIS IS WHAT

GETS BIG WHEN YOU HAVE THE

MUMPS.

SOMETIMES THE LABELS CAN OBSCURE

THE UNDERLYING ANATOMY AND THIS

THAT CASE WE CAN TURN OFF THE

LABELS AND TURN THEM BACK ON

AGAIN SO HERE WE'RE SEEING THE

TONGUE, THE MUSSEL AND--MUSCLE

AND THE KEY.

HERE ARE THE TONSILS.

THIS IS THE SPINAL CORD AND THIS

IS NEAT.

HERE'S THE ANTERIOR FACIAL VAIN

GOING RIGHT INTO THE INTERNAL

JUGULAR VAIN.

HERE'S THE EXTERNAL JUGULAR VAIN

AND BETWEEN THEM, THE STERN O

CLADDOID MUSCLE, AND THAT RUNS

ALONG YOUR NECK, HERE'S THE

TRAPEZUOUS, THAT GOES DOWN TO

THE BACK, SO WE COME DOWN, THIS

IS THE EPIGLOTTIC THAT KICKOFFS

YOUR TRACHEA WHEN YOU'RE

SWALLOWING.

THE SUBMANDIBULAR GRANDS AND IN

HERE WE CAN SEE THIS IS NEAT

TOO, THE CONFLUENCE OF THE

INTERNAL AND EXTERNAL JUGULAR

VAIN AND VOCAL CORDS AND

FINALLY, WE HAVE THE THOI

ROADWAY GLAND SURROUNDING THE

TRACHEA.

SO IF WE GO TO THE FIRST MENU,

WE HAVE THE LATIN, THIS IS THE

LATIN FOR THE STRUCTURES AND

THIS IS USEFUL FOR INTERNATIONAL

USERS.

THIS BOX ICON WILL SHOW THE

TOUCH BOX AROUND THE NUMBERS TO

GIVE YOU THE TOUCH AREA FOR THIS

STRUCTURE DISPLAYED, AND SOME

USERS ASK TO FLIP THE IMAGES AND

SHOW THE MIRROR IMAGE BUT WE

DON'T USE THAT MEDICALLY SO

LET'S LOOK AT THE LATIN OPTION

AND THE BOX OPTION WITH THE

FEMALE PELVIS AND THIS IS FROM

THE VISIBLE HUMAN PROJECT SO

WE'RE SEEING THE TOUCH BOX

AROUND THE NUMBER AND IF IT

TOUCH IT GIVES US THE LATIN NAME

FOR THE STRUCTURE.  AND WE HAVE

ANTERIOR, POSTERIOR, FRONT,

BACK, PATIENT RIGHT, PATIENT

LEFT AND PART OF THE ARM HERE

AND THE HAND.

AND AS WE COME DOWN, WE'RE

SEEING THE PORTION OF THE SECUM,

AND THE SMALL BOWL.

HERE'S THE LATIN NAME FOR THE

ILIAC WING.

THIS IS THE APPENDIX RIGHT

THERE, AND POST MENOPAUSAL

WOMAN, SO HER UTERROUS IS SMALL

AND IT WAS A CADAVER, SO WE SEE

THE COLLAPSED BLATTER AND

FINALLY WE HAVE MULTIPLE QUIZ

MODES AFTER YOU LEARNED YOUR

ANATOMY, THE PROGRAM RANDOMLY

GRABS 10 STRUCTURES FROM THE

DATABASE AND CREATES A GREATED

QUIZ.

SO, LET'S TRY IT OUT AND

HOPEFULLY WITH HELP FROM THE

AUDIENCE, WE'LL TURN TO TO

ENGLISH FIRST.

I'M SORRY.

OKAY.

[LAUGHTER]

AND WE'RE GOING TO DO THE FEMALE

PELVIS SO THE PROGRAM SHOWS THE

NAME OF A STRUCTURE AND THE TOP

AND WE PICK THE CORRESPONDING

NUMBER FROM THE OPTIONS AT THE

BOTTOM.

SO, HERE WE'RE LOOKING FOR THE

FACE WE HAVE A CHOICE OF FIVE,

THREE, FOUR, OR ONE.

ANY--CALL IT OUT?

GO AHEAD?

>> BETSY!

>> ALL RIGHT, LET'S TRY NUMBER

FOUR AND WE HAVE THIS IT NOW SO

THIS IS RANDOM SO THERE'S NO WAY

TO PRACTICE THIS.

WE WILL TRY ONE MORE, HERE IT'S

LOOKING FOR THE QUADRADUS FEMMOR

ISOTOPE.

WE HAVE A CHOICE OF SEVEN, TWO,S

FIVE, AND ONE.

THE.

>> WE'LL TRY NUMBER TWO AND

THERE WE GO.

AND THIS WE CONTINUE AND YOU GET

A SCORE AT THE END.

SO NOW I'VE SHOWN YOU THE

FEATURES OF iANATOMY, WE

LOOKED AT THE FACE AND NECK AND

FEMALE PELVIS AND I LEAVE TO YOU

LOOK AT THE THORAX,

ABNORMALITIES DOMEN AND MALE

PELVIS ON YOUR OWN AND I HOPE

YOU AGREE WITH THE WORDS, THAT

THIS THIS CASE, LESS IS MORE, AT

LEAST WITH THE WORDS OF GLOALDY

LOCKS WITH RESPECT TO THE BABY

BEAR, IT'S JUST RIGHT.

>> ALL RIGHT.

>> [CHEERING]

>> COOL!

>> KD [ APPLAUSE ]

>> SO FOREVER WE MOVE TO THE

NEXT ONE, THIS IS A GREAT

OPPORTUNITY TO TALK ABOUT HOW

THIS PHILOSOPHY OF BOTTOM UP

CHANGE IS PERMEATING ALL OUR

AGENCIES.

WE'RE IN THE MIDST OF AN ACTIVE

COMPETITION OF THE DEPARTMENT OF

EDUCATION, ON BADGES AND THE

PREFASIS THE MAZULAFOUNDATION IS

TO GO THROUGH AND FIND

OPPORTUNITIES LIKE THIS SO IF

YOU WENT THROUGH A QUIZ LIKE

THIS AND YOU COULD COMMUNICATE

YOU DEMONSTRATED MASTERY OF A

DIN TOPIC, YOUR QUIZ COULD GIVE

YOU A CREDENTIAL A BADGE THAT

COULD CARRY WITH YOU AS PART OF

YOUR SECONDARY FORM OF

CREDENTIALLY SO THIS SPIRIT OF

HOW THESE THINGS ALL COME

TOGETHER THIS, IS AN ADVANCEMENT

FOR MEDICAL STUDENTS AND THE

LIKE, MAYBE DINNER PARTY GUESTS,

A FUN GAME SHOW AT OUR HOMES,

BUT IT ALSO TIES INTEREST A

LARGER DISCUSSION ABOUT HOW WE

CHANGE OUR EDUCATIONAL SYSTEMS.

SO I HOPE YOU WOULD APPLY FOR

THAT MAC ARTHUR CHALLENGE ON

BADGES AND LET'S GET ON TO THE

SHOW.

>> FANTASTIC.

>> THE NEXT WINNER IS KNOWLEDGE,

KNALIJ, WHICH LIMITED HELPS
STUDENTS AND

CONSUMERS VISUALIZE DATA SUCH AS

NLMs REPOSITORY PUB MED.

IT'S BUILT AROUND THE IDEA OF

THE BEST PATTERN SYSTEM IN THE

PLANET IS THE PERSON'S OWN

VISUAL SYSTEM, VISUAL MASK CAN

IMPROVE OTHER ABILITIES TO SCAN

LARGE AMOUNTS OF INFORMATION AND

DRAMATICALLY REDUCE THEIR TIME

TO DISCOVERY AND THE TIME TO GET

TO THE CRITICAL INSIGHT THAT

COULD CHANGE EVERYTHING.

KNOWLEDGE WAS DEVELOPED BY ALAN

FINKLE AND LA, AND AS PARTNER

STEPHEN HONORARY VISITING FELLOW

IN THE MELBOURNE AUSTRALIA ANDAL

AN AND MEHRAN NIA ARE NOW HERE

TO DEMONSTRATE KNOWLEDGE.

>> ALL RIGHT!

>> [ APPLAUSE ]

>> OR JUST ME.

>> GOOD MORNING AND THANK YOU

FOR THIS OPPORTUNITY TO

PARTICIPATE AS PART OF NLMs

175th ANNIVERSARY CELEBRATION,

IT IS AN HONOR TO DEMONSTRATE

THE KNOWLEDGE WEB APPLICATION

FOR YOU TODAY.

LET ME START WITH THE WHY,

BEHIND THE KNOWLEDGE

VISUALIZATION APPLICATION.

IT IS OUR BELIEF THE BEST

PROBLEM SOLVING HAPPENS WHEN

PEOPLE COLLABORATE AND INNOVATE

TOGETHER, FINDING SOLUTIONS TO

THE CHALLENGING HEALTH PROBLEMS

WE FACE, LIKE CANCER AND

DIABETES, WILL BE WORKING IN

PARTNERSHIP IN USING THE VAST

STORES AND INFORMATION CALL BIG

DATA AS OUR TOOLS FOR

EXPLORATION.

BIG DATA IS A UNIVERSE OF

POSSIBILITY.

IN 2010, THE WORLD GENERATED

SEVERAL THOUSAND EXOBITES OF

DIGITAL DATA.

SO WHEN IS AN EXOBYTE.

IT IS A CHAIN OF DVDs TO THE

MOON AND BACK.

THAT'S WHAT IT IS.

IT IS WHY THERE IS BIG IN FRONT

OF THE WORD DATA AND THERE IS

MUCH VALUE TO BE DISCOVERED IN

SHARE VOLUME AND COMPLEXITY.

BUT WHAT DOES BIG DATA REALLY?

THAT WE'RE ONLY JUST LEARNING TO

HELP DISCOVER THOSE HIDDEN

SOLUTIONS TO SEE WHAT WE CAN NOT

BEFORE, WE HAVE KNOWLEDGE AND

INFORMATION TO TELESCOPE.

KNOWLEDGE IS AN INFORMATION

TELESCOPE TO HELP US NAVIGATE

LARGE INFORMATION REPOSITORIES

LIKE PUB MED WHICH CONTAIN OVER

20 MILLION JOURNAL CITATIONS.

THIS IS THE WHAT OF KNOWLEDGE.

AN APPLICATION TO DISCOVER MAP,

VISUALIZE AND EXPLORE

INFORMATION.

SO NOW LET ME SHOW YOU HOW

KNOWLEDGE WORKS WITH BIG DATA.

KNOWLEDGE DRESSES DISCOVERY,

MAPPING, VISUALIZING EXPLORING

AND I'LL DEMONSTRATE EACH ASSET

FOR YOU.

SO BEFORE YOU SEE THE FIRST

KNOWLEDGE MATH COME UP AND THE

DEMO, THINK GOOGLE EARTH FOR

DATA WHEN YOU LOOK AT A

KNOWLEDGE MAP.

THE PUB MED CITATIONS ARE LIKE

HOUSES, THE COLORED CIRCLE WHICH

IS WE CALL CLUSTERS ARE LIKE

NEIGHBORHOODS THAT CONTAIN THESE

HOUSES.

IT IS A SIMPLE ANALOGY BUT WILL

HELP YOU UNDERSTAND THE BEAUTY

OF A KNOWLEDGE MAP.

SO LET'S USE IT.

SUSPICIOUS SO A SEARCH GOES OUT

TO PUB MET IN THE TERM AUTISM

AND RETURNS CITATION RESULTS,

THE KNOWLEDGE GROUPS THESE

CITATIONS AND WHAT WE CALL

CLUSTERS IT CONNECTS THE

ARTICLES TO ONE OR MORE CLUSTERS

IN REALTIME.

THE MORE CLUSTERS, THE

LARGER--THE MORE ARTICLES THE

LARGER THE CLUSTER AND THE

COLORS ARE USED TO IDENTIFY

IMPACT FACTOR CLUSTERS AND

CITATION RESULT K'S BE VIEWED IN

THE--AND SORTED IN THE SIDE PAN

AND HE WILL BY CLICKING ON THE

CLUSTER IN THE PANEL, IT TAKES

YOU TO THE CORRESPONDING CLUSTER

WHERE YOU COULD THEN WORK WITH

THE DATA.

WHEN YOU CLICK ON THE CLUSTER,

YOU COULD SEE--YOU'LL SEE HERE,

THE ASSOCIATED ARLS FOR THAT

CLUSTER, IF YOU FOCUS ON THE

CLUSTER, IT'LL ISOLATE THAT

CLUTTER AND ALL RELATED CLUSTERS

OF INFORMATION OR AUTHORS

ASSOCIATED WITH IT.

WE CAN THEN CLICK ON ONE OF

THESE WHICH IS THE ARTICLE AND

IT PULLS UP THE PUB MET ABSTRACT

AND YOU CAN THEN READ THE FULL

ARTICLE.

MOVE ON.

KNOWLEDGE CAN BE USED TO MASK

THE CONNECTION BETWEEN

RESEARCHERS FROM AROUND THE

WORLD.

IN OUR FIRST EXAMPLE, WE'RE

USING THE COLLABORATION FROM

RALPH STEIN MEN, HE WAS THE 2011

NOBEL PRIZE WINNENER MEDICINE

THIS YEAR.

SO BY USING KNOWLEDGE WE CAN SEE

WHO DR. SIMON COLLABORATED WITH

THIS YEAR AND IN WHAT SUBJECT

MATTER EACH COLLABORATION GROUP

FOCUSED SO WE'RE ZOOMING IN.

WE CAN LOOK AT THE DIFFERENT

COLLABORATION GROUPS, VERY

QUICK, AS A SECOND EXAMPLE, HERE

IS THE KNOWLEDGE MASS OF THE

ENTIRE M. I.T. LIFE SCIENCE

NETWORK OF RESEARCHERS.

WE CAN SEE IN REALTIME WHO WERE

THE HUBS OF M. I.T. RESEARCH

THROUGH THE DECADES AND WHO HAVE

BEEN THE LONE WOLVES.

AGAIN THE LARGER ORANGE CLUSTERS

REPRESENT THE„i RESEARCHERS WHO

ARE MOST PROLIFIC AUTHORS AND

THOSE WHO DEVELOPED THE LARGEST

NETWORKS OVER THE YEARS.

MY THIRD EXAMPLE IS VISUALIZE

THE RELATIONSHIP BETWEEN SOCIAL

MEDIA AND RESEARCH.

IN MAY 2010 WILLIAM LEE GAVE A

T. E. D. TALK ON RELATIONSHIP OF

ANGIOGENESIS AND RELATIONSHIP TO

CANCER AND MAYBE INSIGHT IS

GIVEN AT THE TIME HE SPOKE OF T.

E. D. AND WHETHER THE INCREASED

AS A RESPONSE TO THE T. E. D.

TALK AND WE'RE LOOKING AT A

PREDICTIVE QUALITATIVE ANALYSIS.

SO WE LOOK HERE AND THIS IS THE

PAST FIVE YEARS OF ANGIOGENESIS

RESEARCH AND USING OUR TIME

MACHINE FUNCTION WE CAN SEE THE

RELATED PUBLICATIONS WERE FAIRLY

SPARSE UP TO 2009 FOR

ANGIOGENESIS AND THEN HAD A

TREMENDOUS SURGE IN 2010 AND

2011 SO AS CAN YOU SEE THIS IS

THE TIME MACHINE AND YOU SEE THE

ARTICLES EITHER APPEAR OR

DISAPPEAR DEPENDING ON THE

PARAMETERS FOR THE TIME.

SO IT'S FULLY INTERACTIVE AND

THE DATA IS LIVE AND YOU CAN

WORK WITH IT.

FOR MY LAST EXAMPLE WE'RE PROUD

TO SHOW YOU WHAT WE BELIEVE IS

THE FIRST VISUALIZATION OF THE

ENTIRE CORPUS OF CANCER

RESEARCH.

THE LIVING SEARCHABLE

VISUALIZATION TOOL FOR

RESEARCHERS IT'S

APPROXIMATELY--IT COVERS, ONE

MILLION ARTICLES FROM THE 1800S

TO THE PRESENT.

WHERE YOU'RE GOING TO WATCH IS

AN EVOLUTION OF CANCER RESEARCH,

THE VIDEO WILL PAUSE IN THE

EARLY 60S LEADING UP 1964, WHY?

WELL IN 1964 THE SURGEON GENERAL

ANNOUNCED THE CORRELATION

BETWEEN SMOKING AND HEALTH AND

THE RESULT WAS A DRAMATIC

INCREASE IN CANCER PUBLICATIONS

IN PRECEDING AND FOLLOWING 1964

FROM AN AVERAGE OF 4500 NEW

PUBLICATIONS IN THE 1950S TO

ALMOST 16,000 IN 1964 ALONE.

AND THIS IS A TIME LAPSED VIDEO

OF THE PROGRESSION.

WE'RE GOING TO THE 60S BRIGHT

RED CLUSTERS ARE THE MOST

ACTIVE, THE COOLER CLUSTERS ARE

THE MORE DORMANT AND WE CAN GO

ALL THE WAY UP, CUMULATIVELY TO

THE PRESENT AND AGAIN, EVERY

CLUSTER, IF YOU ZOOMED IN WITH

AN--IN KNOWLEDGE, YOU WOULD BE

ABLE TO SEE WHAT SUBJECT MATTER

AND INVESTIGATE ALL THE

ASSOCIATED PUBLISHED CANCER

ARTICLES RELATED TO THAT.

TO CLOSE AS LEONARDO

DISCIPLINARY VINCH OBSERVED LONG

AGO, THE POWER OF VISUALIZATION

IS THE KEY TO UNDERSTANDING THE

WORLD AROUND US AND AFTER 500

YEARS, WE ARE STARTING TO CATCH

UP.

THANK YOU.

[ APPLAUSE ]

>> HEY, ALAN CAN I GIVE YOU A

HOME WORK ASSIGNMENT.

WE'RE RELEASING AS MUCH ECONOMIC

DEVELOPMENT DAT AS POSSIBLE, IT

MIGHT BE INTERESTING TO OVERLAY

THE PUBLICATION CLUSTERS AND THE

KNOWLEDGE NETWORKS WITH JOB

CREATION AND START UP ACTIVITY.

>> GIVE US THE DATA AND WE'LL

VISUALIZE IT.

>> YES, SIR YOU WILL!

LET'S FIGURE IT OUT!

>> FANTASTIC!

>> FANTASTIC!

>> THE NWINNER IS NLMPLUS, A

STOEVERY APP SIMULTANEOUSLY

SEARCHES 59 NLM DATABASES TO

EXPLORE THE CONTENT RICH

OFFERINGS ACROSS ALL AREAS OF

BIOINFORMATION AND MEDICINE AND

ENABLE THE BROADEST SPECTRUM OF

USERS AND DEFINE HEALTH INFO VIA

SIMPLE AND YET POWERFUL

INTERFACE.

IT WAS DEVELOPED BY WEBLIBB LLC,

USING RESTEVAL TOOLS AND

SOLUTIONS.

ANTONIO ZAMORA AND ADAM VINCENT,

AND WEIZHONG ZHU, JOIN US TO

DEMONSTRATE.

>> COME ON UP.

>> ALL RIGHT!

>> I AM NOT ADAM VINCENT, I AM

TOM, I RECEIVED A CALL FROM ADAM

AT 8:00, HE HAD A FLAT TIRE ON

i-270.

THE NLM PLUS TEAM WHO DID THE

WORK FACED OTHER CHALLENGES.

WEIZHONG IS HERE, LEAVING A

FAMILY OF OF TWO KIDS AND HIS

WIFE WITHOUT ELECTRICITY

FOLLOWING LAST WEEK'S WINTER

STORM IN THE FALL.

TONY CAME BACK FROM ITALY WITH

LARYNGITIS AND HE LUCKILY IS

RECOVERING.

SO, IT'S QUITE AN ADVENTURE.

NOW I AM VERY GLAD TO HELP OUT

BECAUSE I RETIRED FROM THE

NATIONAL LIBRARY OF MEDICINE

LAST FALL AND I'M REALLY, REALLY

HAPPY TO HAVE WORKED HERE AND BE

BACK, SO IT'S GOOD TO BE HERE

BUT THEN AGAIN, QUOTING THE

GREAT KEITH RICHARDS AT THE

ROLLING STONES CONCERT IN LAS

VEGAS.

IT'S GOOD TO BE ANYMORE THESE

DAYS.

--IMEERP, THESE DAYS--ANYWHERE

THESE DAYS.

[LAUGHTER]

SO IF I MAKE TAKES--MAKE

MISTAKES, BEAR WITH ME.

SO NLMPLUS WAS A VERY

INTERESTING CHALLENGE FOR THIS

TEAM AND I WISH I COULD HAVE

PARTICIPATED ACTIVELY BUT I WAS

TOO LATE AND THESE TWO GENTLEMAN

HERE DID ALL THE ACTUAL WORK ON

THE SIM ANT ASPECTS OF WHAT NLM

PLUS DOES.

SO WHAT IS NLM PLUS, IT'S A

SYMANTIC ENGINE AND KNOWLEDGE

APPLICATION THAT ESSENTIALLY

TRIES TO TAP INTO THE MOST

IMPORTANT¨— DATABASES AND APIs

AND WEB SERVICES OF THE NATIONAL

LIBRARY OF MEDICINE.

SO, LET'S SEE IT IN ACTION.

IF I TYPE IN A SEARCH QUERY LIKE

GOUT, THEN THE INFORMATION THAT

COMES BACK COMES FROM A VARIETY

OF HETEROGENEOUS NLM DATABASES

AND SO, IF I LOOK AT THE HEALTH

TOPIC THAT I JUST ENTERED AND

LOOK AT GOUT, I GET BACK A

TYPICAL MEDLINE PLUS ARTICLE ON

THIS TOPIC.

IF YOU--IF YOU LOOK AT OTHER

TYPES OF INFORMATION THAT ARE

INTEGRATED HERE, DRUG AND

SUBSTANCES, SIMILARLY YOU GET

INFORMATION FROM THE MEDLINE

PLUS SYSTEM ON THIS PARTICULAR

DRUG.

AND I WOULD LIKE TO SHOW YOU

SOME OF THE INNOVATIVE ASPECTS

OF THIS SYSTEM.

IF YOU CLICK ON THE ALL NLM PLUS

DATABASES THEN I SEE THE HIT

COUNTS FROM ALL 59 DATABASES

THAT WERE INCLUDED HERE AND THIS

IS VERY NICE FEATURE BECAUSE THE

SYSTEM AIMS TO ACCOMMODATE A

WIDE VARIETY OF USERS, SO,

BIOMEDICAL RESEARCHER MAY BE

INTERESTED IN GENES AND

INTERESTED IN MAYBE CLINICAL

TRIALS AND IF YOU ACTUALLY GO TO

ANY OF THESE SYSTEMS, YOU HAVE

THE TREMENDOUS POWER OF THAT

NATIVE INTERFACE, SO YOU CAN

LOOK AT WHATEVER THE CLINICAL

TILES APPLICATION IS DOING, AND

SO, THE INTERFACE COMBINES THE

POWER OF NATIVE SEARCHING, OF

THE INDIVIDUAL DATABASES, AND

SOFTWARE AND HARDWARE AS WELL

AS, THE COMMON INTEGRATIVE

INTERFACE.

AND THIS PROBLEM IS NOT UNIQUE

TO THE NATIONAL LIBRARY OF

MEDICINE.

A LOT OF ORGANIZATIONS OF ALL

KINDS HAVE DIFFERENT DATABASES

ON DIFFERENT PLATFORMS ON

DIFFERENT TIME SPECIALIZATION OF

SPECIFIC ENDOTHELIAL WE WANT TO

INTEGRATE THE INFORMATION ON

BEHALF OF THE USERS FROM A

VARIETY OF SOURCES.

SO WE COULD THINK OF DHHS PLUS

APPLICATION, WE COULD THINK OF

NIH PLUS APPLICATION, AT GOV

PLUS APPLICATION AND SO ON.

TAPPING INTO THE DATABASES.

ANOTHER INNOVATIVE ASPECT OF THE

NLMPLUS APPLICATION IS THE

RECENT PUB MED REVIEWS SEARCH.

SO HERE YOU HAVE--YOU HAVE A

BASICALLY THE RESULT OF A

SEMANTIC SEARCH WHERE THE TEAM

TOOK THE LAST THREE YEARS OF PUB

MED REVIEW ARTICLES, INDEX THEM

USING SYMANTIC TECHNOLOGIES AND

MADE THEM AVAILABLE FOR

SEARCHING ON AN OPEN SOURCE

PLATFORM AS YOU WILL HEAR LATER

ON.

AND FINALLY, I WOULD LIKE TO

POINT OUT THAT THE EXPLORE AND

DISCOVER DATA, THE HEALTH

CONCERNS ASSOCIATED WITH YOUR

TOPIC TEST TREATMENT, DRUG STUB

STANCES, ET CETERA COMES FROM

THE KNOWLEDGE BASE THAT DRIVES

THE SYMANTIC SEARCH AS WELL AND

ALLOWS USERS TO EXPLORE AND

DISCOVER TOPICS ASSOCIATED WITH

THE USERS INTERESTS AND YOU CAN

MODIFY THE SEARCH AND SO ON.

AND THIS PARTICULAR KNOWLEDGE

BASE HEAVILY UTILIZES THE

NATIONAL LIBRARY OF MEDICINE

UNIFIED MEDICAL LANGUAGE SYSTEM.

IT'S THE KEY PIECE OF IT AND

IT'S ALSO INCORPORATES

INFORMATION FROM OTHER RELIABLE

TRUST WORTHY SOURCES ON THE WEB.

AND SO, I WOULD LIKE TO POINT

OUT ONE MORE FEATURE WHEN YOU DO

A SEARCH AND LET'S GO--SOME SORT

OF A DIFFERENT TOPIC--YOU WILL,

OKAY, ONLINE SYSTEMS, OKAY.

THEN OVER ON THE RIGHT HAND

SIDE, YOU ACTUALLY SEE THE FIRST

RECORD FROM EACH OF THE SOURCES

OF THE INFORMATION.

SO AT A GLANCE, YOU CAN SEE WHAT

TYPE OF INFORMATION FOR EXAMPLE,

YOU MAY WANT TO LOOK AT

THE--OKAY, THE NEWS AND YOU SEE

AN ARTICLE ON KIDNEY STONES TIED

TO HIGHER DIABETES RISK AND SO

ON.

AND YOU CAN CLICK AND SO ON.

AND SO WE HOPE HAVE YOU A CHANCE

TO EXPLORE AND DISCOVER NLM PLUS

AND IT'S WONDERFUL RESOURCES.

SO, SO WEIZHONG, WILL WILL

DESCRIBE THE DETAILS OF THE

SYMANTICCANONATION AND INDEXING

OF THIS RECENT PUB MED REVIEW

RESEARCH APPLICATION.

AND BEFORE I TURN IT OVER, I

JUST WANT TO READ A SIMPLE

DEFINITION OF SIM ANTIC SEARCH

IN THE CONTEXT OF SEARCHING

TEXTURAL DATABASES.

FIRST OF ALL YOU DEAL WITH KEY

WORDS--NOT KEY WORDS BUT

CONCEPTS, AND IT'S ANY TYPE OF

APPROACH THAT PRODUCES

MEANINGFUL RESULTS, EVEN IF THE

KEY WORDS ARE NOT IN YOUR QUERY

OR THERE'S NO QUERY AT ALL LIKE

WHEN YOU POINT YOUR CELL PHONE

AT SAY THE WHITE HOUSE AND GET

INFORMATION ABOUT THE WHITE

HOUSE.

IT'S A SYMANTIC SEARCH

APPLICATIONS LIPICATION AND THE

PURCHASE THING TO BEAR IN MIND

AND THIS WAS BROUGHT HOME TO ME

IN THE LAST THREE-FOUR YEARS IS

IN MY CAREER HERE AT THE

NATIONAL LIBRARY OF MEDICINE,

LARGELY AS A COMPUTER SCIENTIST

WORKED WITH DATABASES AND

MONITOR EPIGENETICCULATED KEY

WORDS AND SO ON.

--MANIPULATED KEY WORDS AND SO

ON.

BUT NOW I BED THE MEANING OF

CONCEPTS LIKE GOUT, AS I DEAL

WITH THE SIDE EFFECTS OF DRUGS

AND DEAL WITH SOME OF THE

SYMPTOMS AND SO ON.

SO IT'S A BIG, VERY REAL

DIFFERENCE.

SO I WOULD LIKE TO TURN IT OVER

TO WEIZHONG TO INTRIEB THE

ANNOTATIVE APPROACH.

>> THANK YOU TOM, THANK PERCENT

THE GREAT INTRODUCTION.

THE--THANK YOU FOR THE GREAT

INTRODUCTION.

>> HE INTRODUCED THE GENERAL

PROCEDURES OF SYMANTIC

ANNOTATION, HERE IN THE REVIEW

ARTICLE WITH TITLE AND ABSTRACT,

WE USE OUR PUB SPEED AND

SEARCHER TO ANNOTATE THE TITLE,

I USE IT AS AN EXAMPLE, OUR

CHUNKER ABSTRACTS ALL THE

POSSIBLE NAME PHRASE FROM THE

TITLE, IDENTIFY THE CLIPPINGS

AND THE KEY PHRASE MAYBE TO THE

MOST CONCEPTS AND ADDING THE

INFORMATION SUCH AS A NAME FROM

OUR BIOMEDICAL KNOWLEDGE BASE.

>> THEN THESE KEY CONCEPT UNDER

THE KEY PHRASE ARE NORMALIZED

FOR INDEXING ALL QUERY

TRANSLATION.

FOR EXAMPLE, HERE THE PPIN IN

TITLE PHRASE IS TO YOUR MS

CONCEPT, BREAST CARCINOMA, AND

IT HAS A SYNONYM BREAST TUMOR.

SO, MY COLLEAGUE TONY WILL

INTRODUCE HIS AV DICTIONARY

SYSTEM HOW TO USE THE SYSTEM TO

NORMALIZE THE PHRASE ON THE

CONCEPT FOR SYMANTIC INDEXING

AND THE STORY TRANSLATOR.

>> THANK YOU.

>> ONE OF THE THINGS YOU WILL

NOTICE IS THAT THE GENERATION OF

THE NORMALIZED SYMANTIC INDEX

SYSTEM ACCOMP LIRKED BY THE

ANALYSIS TOO THAT USING SEVERAL

NATURAL LANGUAGE PROCESSING

ALGORITHMS INCLUDING

INFLECTIONAL AND MORPHATIONAL

TECHNOLOGY.

THIS ENGINE USES THE SEARCH

ENGINE SYSTEM WHICH IS

CUSTOMIZED WITH SIM ANTIC SEARCH

LAYER AND THE DEVELOPED BY A

MEDICAL KNOWLEDGE BASE.

WE TESTED THE SCALABILITY OF

WEBLESS SYMANTIC SOLUTION BY

IMPLEMENTING THE SEARCHING AND

INDEXING OF 1.6 MILLION PUB MED

REVIEWS ON A SMALL NLM PLUS DISK

SERVER AND THE NEXT SLIDE SHOWS

AN NLM PLUS YSNANTIC SEARCH AND

THE PROSTATE ANTIGEN THREE.

NOW ONE OF THE THINGS YOU WILL

NOTICE, IS THAT THE RESOURCES

INCLUDE THE TERM PCA THREE WHICH

IS DERIVED FROM THE SYNONYMS

DISCOVERED DURING THE QUERY

PROCESSING AND THIS PARTICULAR

SEARCH PRODUCED FOR A RELEVANT

RESULTS.

SEARCH OF COMPLEX TRANSWENT

BLINDNESS AS THE ANGIOGRAPHY

IDENTIFIES MULTIPLE CONCEPTS
CONCEPTS AND

ACHIEVES FOUR REVIEW ARTICLES IN

NLM PLUS AND THE CONCEPTS ARE

IDENTIFIEDED BY HIGHLIGHTING

WHEN THEY ARE FOUND HERE AND THE

FEATURES AND INNOVATIONS OF NLM

PLUS INCLUDE THE UNIVERSAL

SEARCH, SYMANTIC SEARCH MEDICINE

AND INTUITIVE USE OR INTERFACE

WHICH IS APPLICABLE TO A WIDE

SPECTRUM OF USERS FROM TYPICAL

CONSUMERS TO RESEARCH

PROFESSIONALS.

AND AND IN ADDITION WE'RE

GRADUALLY EXPANDING THE

KNOWLEDGE BASE AND WE'RE ALSO

LOOKING AT WEB KNOWLEDGE BASE TO

SUPPORT MEANINGFUL MOONINGFUL

APPLICATIONS OF SCIENCE AND

TECHNOLOGY, THE SEARCHING OF OF

THE HETEROGENEOUS DATABASES IS

THROUGH A LARGE ORGANIZATION AND

WE FEEL THAT NLM PLUS PROVIDES A

MEANINGFUL APPROACH TO THIS

UNIVERSAL PROBLEM NOW PLEASE TRY

NLMPLUS AND GIVE US YOUR

FEEDBACK.

THANK YOU.

KD AAPPLAUSE.

[ APPLAUSE ]

>> YOU KNOW TODD TREMINDS ME,

THE PRESIDENT ISSUES AN

EXECUTIVE ORDER CALLING ON MORE

CUSTOMER SERVICE FEATURES AS

FOLKS INTERACT WITH THEIR

GOVERNMENT, SIMPLIFYING SEARCH

ACROSS ALL THE DATABASES

QUALIFIES, SO WE HAVE A CUSTOMER

SERVICE ENHANCEMENT AS WELL.

>> AND LAST BUT NOT LEAST,

QUERTLE IS AN APP THAT USES

DOCUMENTS AND IT IS GEARED TO

ACTIVE LIFE SCIENCE

PROFESSIONALS, RESEARCHERS AND

HEALTHCARE PROVIDERS AND

DESIGNED TO SAVE THEM A TON OF

TIME AND EFFORT IN FINDING KEY

LITERATURE THEY NEED.

JEFF SAFFER AND VICKI BURNETT

LED FROM COLORADO THEY WILL NOW

SHOW YOU WHAT THEY'VE DONE.

>> ALL RIGHT.

>> WELCOME!

SPHWHRKS

>> WELCOME!

[ APPLAUSE ]

>> THIS IS VICKI BURNETT AND

JEFF SAFFER, THANK YOU TO

EVERYONE FROM THE NLM.

WE ARE THRILLED TO BE HERE FOR

THIS, WE ARE NOT ONLY THANKFUL

FOR THE AWARD BUT FOR THE

RESOURCES THAT NLM PROVIDES THAT

MAKE THIS IS TYPE OF AMPLICATION

POSSIBLE.

JEFF AND I HAVE BEEN LONG

TERMING SCIENTIST SYSTEM HAVE

EXPERIENCED FIRST HAND THE

EXPLOSION OF INFORMATION THAT IS

AVAILABLE.

AND OF COURSE, THEN THE

RESULTING DIFFICULTY AND

ACTUALLY FINDING THE DOCUMENTS

THAT ARE MOST RELEVANT TO A

SPECIFIC QUERY.

SO TO ADDRESS THIS ISSUE, WE

HAVE INTEGRATED OUR EXPERIENCE

IN TEXT MINING WITH A BIOMEDICAL

BACKGROUND AND WE HAVE NOW

PROVIDED A FREE NOW RESOURCE

THAT CAN DRAMATICALLY REDUCE THE

TIME AND EFFORT REQUIRED TO

DEFINE RELEVANT DOCUMENTS AND

JEFF IS GOING TO DO A BRIEF LIVE

DEMO OF THE QUERTLE WEB SITE TO

SHOW YOU HOW WE DO THAT.

BEFORE WE GET STARTED BECAUSE IT

MAY BE A LITTLE TOUGH TO SEE THE

WEB SITE, WE HAVE ACTUALLY

ZOOMED IN TO SEE THIS SO THE WEB

SITE YOU SEE ONLINE IS A LITTLE

BIT BIGGER BUT THIS IS ALREADY

ZOOMED IN, ISN'T IT?

MAKE SURE EVERYONE CAN READ THE

QUERIES HERE IN THE BACK AND IN

THE CAST.

>> ALL RIGHT.

SUPPOSE WE'RE INTERESTED IN

CAFFEINE AND DISEASE?

IF WE WERE TO DO A TRADITIONAL

KEY WORD SEARCH AND FIND THE

DOCUMENT THAT CONTAINED THESE

TWO WORDS, IF WE WERE FOR

EXAMPLE, IN A FULL TEXT

DOCUMENT, CAFFEINE MIGHT BE IN

THE INTRODUCTION, DISEASE MAY BE

MENTIONED SOMEWHERE IN MATERIALS

AND METHODS, THE DOCUMENT ISN'T

REALLY ABOUT CAFFEINE AND A

RELATIONSHIP TO DISEASE, SO THE

RESULT IS, WE OFTEN GET VERY

LONG LIST OF RESULTS AND SPEND

MOST OF OUR TIME GOING THROUGH

THOSE TO TRY AND FIND THE ONES

THAT ARE REALLY RELEVANT TO WHAT

WE'RE ASKING ABOUT.

SO INSTEAD, WHAT WE'RE DOING AT

QEURTLE, IS TO DISSECT EACH

SENTENCE IN EVERY DOCUMENT TO

FIND WHETHER THE AUTHOR HAS

ACTUALLY STATED A RELATIONSHIP

BETWEEN--IN THIS CASE, CAFFEINE

AND A DISEASE.

CAUSES THE DISEASE, CAFFEINE

PRESENTS THE DISEASE AND SO ON.

THE RESULT IS BY DOING THIS

ADVANCED LINGUISTIC SEARCH,

LOOKING FOR THOSE AUTHOR

ASSERTIONS INSTEAD OF GIVING YOU

THE LONG LIST, WE GIVE YOU THE

LIST THAT'S ACTUALLY RELEVANT TO

START WITH SAVING YOU A LOT OF

TIME.

THE IN ORDER TO DO THIS, WE USE

A LOT OF LINGUISTIC METHODS,

INCLUDING SIM ANTICS AND

ONTOLOGYS AND WHAT YOU'VE HEARD

ABOUT AND WE GO BEYOND THAT TO

ACTUALLY UNDERSTAND WHAT THE

AUTHOR ASSERTIONS ON ARE.

NOW I WANTED TO POINT OUT THAT

OFTEN TIMES A QUERY FOR A WORD

LIKE DISEASE, OR PROTEIN OR

CHEMICAL ISN'T ALL THAT

EFFECTIVE FROM THE LITERATURE

BECAUSE THESE TERMS OCCUR SO

OFTEN IN THE BIOMEDICAL

LITERATURE.

>> WHAT YOU'RE INTERESTED IN IS

ACTUAL DISEASES, GENE NAMES,

BIOLOGICAL PROCESSS AND SO ON.

SO IN THIS CASE, WE'RE GOING TO

CHANGE THIS QUERY, JUST

SLIGHTLY, AND THIS DOLLAR SIGN

DISEASE IS ONE OF QUERTL'S

PREDEFINED SEARCHES, INSTEAD OF

SEARCHING FOR DISEASE OR

ABNORMALITY, SEARCH FOR ACTUAL

DISEASES INSTEAD SO GO AHEAD AND

EXECUTE THIS QUERY.

THANK YOU FOR SCROLLING OVER

THERE, VICKI.

SO WHAT WE GET IS A LIST OF THE

RESULTS, BY DEFAULT THESE ARE IN

ORDER OF RELEVANCE TO YOUR

QUERY.

BUT WHAT WE SHOW YOU HERE IS THE

ASSERTION OR ASSERTIONS BY THE

AUTHOR THAT MADE THIS DOCUMENT

RELEVANT TO YOUR QUERY IN THE

FIRST PLACE.

FOR EXAMPLE, WE HAVE HERE THAT

CAFFEINE CAUSES NEURAL TUBE

DEFECTS, OR IN THE SECOND

EXAMPLE, CAFFEINE TRIGGERED

REACTIVE OXYGEN SPECIES

FORMATION.

IN THE QEURTLE, DISEASE MEANS

ANYTHING THAT IS PHYSIOLOGICALLY

BAD, SO ENHANCE ROS FORMATION

HERE AS WOULD BE SOMETHING LIKE

MUTATIONS SO WHAT WE NOW HAVE

ARE THE RELEVANT DOCUMENTS RIGHT

AWAY, AND YOU CAN SEE THOSE

AUTHOR ASSERTIONS HIGHLIGHTED IN

CONTEXT, IMMEDIATELY KNOW WHY

THIS DOCUMENT IS HERE AND WHICH

ONES ARE RELEVANT.

BUT NOW WE NEED TO GO BEYOND

JUST FINDING THIS LIST.

IT IS ALSO IMPORTANT TO HAVE AN

EFFECTIVE MEANS TO EXPLORE AND

TRILL DOWN THROUGH THIS SET OF

DOCUMENTS.

HERE ON THE LEFT-HAND SIDE, OR

PATIENT RIGHT, I GUESS.

WE HAVE A SET OF EASY TO USE

DYNAMIC FILTERS WHERE YOU CAN

SIMPLY CLICK AND HAVE THE SET OF

DOCUMENTS SHOW UP IN THE UPDATE.

IN ALSO CONTAINING FILTER, YOU

CAN ADD ADDITIONAL FINDING TERMS

WITHOUT HAVING TO NARROW THIS

DOWN AND GO OFF AND RECREATE THE

QUERY AGAIN, PUBLISHED WITHIN,

SIMPLY CLICK AND HAVE THAT

UPDATE.

PUBLICATION TYPE, COVERS THINGS

LIKE REVIEWS, FULL TEXT

DOCUMENTS, GRANT APPLICATIONS,

ONE OF THE THINGS ABOUT THE

QUERTLE SEARCH ENGINE IS WE ARE

SEARCHING AT ONE TIME, EXPANDING

FULL TEXT DOCUMENTS, THE TOX

LINE DATABASE WHICH COMES FROM

NLM, NEWS ARTICLES AND MORE.

SO WHAT I LIKE TO SPEND MOST

TIME ON IS TALK ABOUT THIS KEY

CONCEPT FILTER WHICH IS UNIQUE

TO QUERTL.

THESE KEY CONCEPTS THAT ARE

LISTED AS THESE DRILL DOWN

FILTERS ARE DERIVED FROM THE

ASSERTIONS THAT WERE MADE BY THE

OFFER AND FOUND BY THE QUERY.

IN THIS PARTICULAR CASE SINCE WE

USED ONE OF OUR POWER TERMS FOR

DISEASE, WHAT WE SEE ARE A LIST

OF THE DISEASES THAT ARE SOMEHOW

AFFECTED BY CAFFEINE.

AGAIN WHAT THE NATURE OF THAT

IS, WE DON'T YET KNOW, BUT

THESE--THIS IS IN FACT A LIST OF

THE DISEASE THAT HAVE SOME

ASSOCIATION WITH CAFFEINE.

WE NOW HAVE AN ANSWER TO A

QUESTION SO IN FACT, THIS KEY

CONCEPT FELTER IS A WAY--FILTER

IS TO GET A WAY TO WHAT GENE

PROCESS AND SO ON.

SO WE HAVE A SET OF KEY CONCEPTS

THAT ARE JUST GENERAL AND AND

RISK.

AT THE BOTTOM YOU CAN SEE WE

HAVE A SEPARATE SECTION THAT

COVERS THE VERBS.

THIS IS THE ACTION THAT TIES

CAFFEINE TO A DISEASE.

FOR EXAMPLE, PREVENT AND IF WE

CLICK ON PREVENT, NOW THE SITE

UPDATES AND SHOWS YOU JUST THE

DOCUMENTS THAT WERE ABOUT

CAFFEINE AND DISEASE AND

SPECIFICALLY WHERE CAFFEINE

PREVENTED SOME DISEASE AND WE

CAN SEE ASSERTIONS SUCH AS

CAFFEINE PREVENT TED NEURONAL

DAMAGE IN THIS PARTICULAR

INSTANCE OR CAFFEINE PREVENTED

HYPERTENSION OR SUCH AND SUCH AS

A DISEASE WAS PREVENTED BY OR

WHATEVER THE TERMINOLOGY IS, IT

DOESN'T MATTER WE USE THE

LINGUISTICS TO FIND WHAT IS

RELEVANT.

SO THE POWER OF THIS METHOD IS

THAT THE RELATIONSHIP SEARCHING

FOCUSING ON THE SEARCHING SAVES

YOU TIME WITH THE AUTHOR BY

GETTING YOU THE RELEVANT

DOCUMENTS RIGHT AWAY AND HAVING

AN EASY TO USE INTERFACE TO

EXPLORE AND DRILL DOWN GETS YOU

WHAT YOU NEED AND IT'S VERY

SIMPLE FOR EXAMPLE TO EXPORT

THESE RESULTS INTO ANY

BIBLIOGRAPHIC MANAGEMENT

SOFTWARE AND OTHERWISE INTERACT

WITH THIS GOING FORWARD.

>> AND I'D JUST LIKE TO REMIND

EVERYONE THIS IS A FREE RADICALS

RESOURCE WE WE ENCOURAGE

EVERYONE TO GO TO THE

QUERTLE WEB SITE AND GIVE IT A

TRY.

>> MICKEY:  THANK YOU.

>> THANK YOU.

[ APPLAUSE ]

>> CAN I SAY ONE MORE THING

BROTHER TOTTED, ARE YOU THINKING

ABOUT LARCHING THIS AS A

COMMERCIAL APPLICATION?

IS IT A START UP OF SORTS.

>> QUERTLE, IT IS A

COMMERCIALENTITY, WE'RE

CURRENTLY ADVERTISING SUPPORTED

AND ALSO INTERESTED IN FINDING

PEOPLE THAT WANT TO DEPLOY THESE

TECHNOLOGIES IN OTHER SYSTEMS?

>> WHY DID I ASK THAT QUESTION,

TODD PARK, THE REASON IS BECAUSE

LITERALLY NEXT WEDNESDAY I'M

COMING TO BOULDER BECAUSE WE'RE

LAUNCHING START UP COLORADO WITH

BRAD FELLED AND PHIL WISER AND

THE TEAM AND THE SPIRIT OF THIS,

AGAIN, SECONDARY BENEFITS OF THE

NLM APPs CONTEST IS THAT THIS

KIND OF CREATIVITY AND

ENGINEUITY HAS COMMERCIAL VALUE

AS ALL THE APPLICATIONS

DEMONSTRATED TODAY AND THAT

LAUNCHING NEW PRODUCTS AND

SERVICES TO GROW THE AMERICAN

ECONOMY IS ANOTHER KEY BENEFIT

OF THEAC ACTIVITIES--OF THE

ACTIVITIES SO I HOPE YOU'RE

COMING WEDNESDAY IF NOT WE'RE

CLOSE TAG LOOP AND IN 2.2

SECONDS.

CONGRATULATIONS TO ALL THE

WINNERS.

>> [ APPLAUSE ]

>> BEFORE WE OPEN UP, JUST A

SHOUT OUT TO EVERYTHING THAT NLM

IS DOING TO MAKE THIS POSSIBLE,

I THINK THAT SO MUCH OF WHAT

YOU'RE DOING EXEMPLIFY WHAT IS

WE'RE DOING AS A DIDN'T WITH THE

HEALTHY INITTIA AT A AND IT'S

NOT JUST MAKING DATA AVAILABLE,

IT'S MAKING IT ACCESSIBLE,

READABLE, COMPUTABLE, INGESTIBLE

BY FOLKS LIKE THIS, PUTTING

EPIs ON IT, SO LAUNCHING IT

AND TAKES THE INCREDIBLE MEDLINE

PLUS AND TURNS IT INTO CHUNKS

THAT CAN BE BEAM INTOED THESE

DIFFERENT APPZ AND GET THE WORD

OUT TO INNOVATORS KNOW THEY

EXIST TO GET THEM TO SCRUB IN

AND AT NO COST TO TAXPAYERS AND

BUILD INCREDIBLE STUFF THAT THEN

NOT JUST APPROVE THE HEALTHCARE

BUT APPROVE JOBS AND IT'S JUST

AWESOME SO IN CELEBRATION OF THE

AMAZING INGENUITY BY THE ALL THE

WINNERS AND THESE RUN FOR NLM

FOR THIS, DOING INCREDIBLE WORK

OVER IT.

>> KD APLAYS PLACES.

>> AND TO TODD'S POINT,

LITERALLY IN JUNE, I SENT A MEMO

TO EVERY CABINET HEAD

CELEBRATING 10 BEST PRACTICES OF

OPEN INNOVATION, THE NLM PORTAL

WAS PROMINENTLY FEATURES SO

THANK YOU VERY MUCH.

[ APPLAUSE ]

>> SO WE DO HAVE TIME, GREAT

APPLICATIONS AND GREAT

DEMONSTRATIONS AND GREAT

ATTENTION TO TIME FRAME.

SO IT'S FABULOUS.

AND WE DO HAVE TIME FOR

QUESTIONS IF ANYBODY HAS SOME

AND THEN SOMEBODY CAN TELL ME IF

WE HAVE QUESTIONS OUT FROM

TWITTER AS WELL.

ANYONE HERE HAVE ANYTHING THEY

WISH TO ASK OUR DISTINGUISHED

PANEL OF INNOVATORS?

>> YES?

>> MISS STEIN, YOU MENTION THAD

APP USERS TYPICALLY USE AN

APP FOR TWO MINUTES.

>> YES, LESS THAN TWO MINUTES.

>> WERE THERE ANY OTHER

INTERESTING CHARACTERISTICS THAT

YOU INCORPORATE INDEED YOUR

PRODUCT.

>> THE QUESTION WAS ARE THERE

ANY--CHARACTERISTICS OF

APP USERS, ADDITIONALLY TO THE

TWO MINUTES?

>> MOST PEOPLE WILL DOWNLOAD AN

APPAND USE IT ONCE AND NEVER USE

IT AGAIN.

SO ONLY 25% WILL THEY EVER USE

IT AGAIN AND AFTER HAY MONTH,

ONLY FIVE% OF APPSARE GETTING

USED AT ALL.

SO IT REALLY, IT NEEDS TO BE

USEFUL, IT NEEDS TO BE SIMPLE,

IF IT'S TOO MUCH, PEOPLE GET

FRUSTRATED, THEY MOVE ON TO THE

NEXT THING.

>> YES?

PRESS YOUR MIC THERE.

>> THIS IS FOR JEFF AND VICKI,

YOU MENTIONED ONE TERM FOR POWER

AND DISEASES, DO YOU HAVE OTHER

POWER TERMS.

PROTEINS, CHEMICALS, BIOLOGICAL

PROCESSES, ON THE WEB SITE, JUST

UNDERNEATH THE SEARCH BOX IS A

LINK TO A LIST OF POWER TERMS,

THE ONES THAT ARE MOST COMMONLY

USED BY OUR USERS CURRENTLY ARE

LISTED RIGHT THERE ON THE FRONT

PAGE AND THEN THERE'S A SUBLINK

THAT WILL TAKE YOU TO A LONG

LIST OF OTHER POWER TERMS.

>> I WILL ADD THAT ALL OF THOSE

POWER TERMS WERE CREATED BY

REQUEST FOR FR USERS.

SO IF WE DON'T HAVE WHAT YOU

WANT, LET US KNOW.

>> ANY OTHER QUESTIONS HERE.

>> ONE MORE FOR JEFF, HERE'S AN

EXAMPLE YOU GAVE ON CAFFEINE AND

DISEASE AND, AND WHEN WE DO

QUERIES, YES, WHAT WE DO IS

AUTOMATICALLY LOOK FOR ALL THE

RELATED TERMS AND CONCEPTS.

AND THAT PARTICULAR CASE, WE

PROBABLY DO NOT PRECISELY LOOK

AT CAFFEINE BEING EQUAL TO

COFFEE, IT'S A SUBCOMPONENT OF

COFFEE BUT IN GENERAL, IF YOU'VE

HEARD A SEARCH FOR SOMETHING

LIKE AGING, YOU WOULD FIND NOT

ONLY THE DIFFERENT SPELLINGS OF

AGING BUT ELDERLY, SIN ESTIMATE

THAD ENS, LONGEVITY AND THINGS

THAT ARE RELATED AUTOMATICALLY

WITHOUT HAVING TO DO

COMPLICATING THIS OR THIS OR

THIS OR THIS.

>> ANYONE ELSE?

>> YES, JERRY?

>> SO I THOUGHT ALL THE

APPLICATIONS WERE VERY, VERY,

COOL AND INTERESTING AND THEN

THANK YOU FOR I THINKING THEM TO

US, I GUESS YOU MET THE DEADLINE

FOR GETTING THEM IN ON TIME AND

YOUR APPs ARE SUBMITTED BUT MY

QUESTION IS WHAT'S NEXT?

ARE THEY ALL UNDER TWEPMENT OR

NEW FEATURES COMING IN OR WHAT'S

THE NEXT STEP.

>> THAT'S EVERYONE, WE CAN START

AT THE OTHER END AND PRESS YOUR

MIC.

>> SO FOR YOU WHEN WE DESEENED

THE SYSTEM WE TRY TO MAKE IT

MONITORED SO WHEN WE HAVE THE

LIST OF GENE WE START THINKING

WHERE TO SEND IT TO AND YOU WHAT

INFORMATION, ESPECIALLY LIKE

FUNCTIONAL ENRIVERMENT OF

PROTEIN PROTEIN NETWORKS WHAT

THE USER NEEDS TO DO WITH IT AND

THAT WILL BE OUR NEXT STEP.

>> iANATOMY IS GOING TO BE

DEVELOPED INTO AN iPAD APP AND

REALLY TO TAKE ADVANTAGE OF THE

FEATURES OF THE IPADS THAT ARE

DIFFERENT FROM THE iPHONE, AND

ALSO WITH MY FIRST APP LEARNED A

LOT SINCE THEN AND I WANTED TO

UPGRADE IT AND JUST MAKE IT

BETTER, MAKE IT MORE COMPLIANT.

>> WE ASSIGNED KNOWLEDGE AS A

FRAMEWORK, AS A PLATFORM FOR BIG

DATA SO WHETHER IT'S PUB MED OR

WHETHER IT'S ANY OTHER LIFE

SCIENCE MEDICAL, ANY OTHER TYPE

OF DATA, WHETHER IT'S WIKIPEDIA

OR ANY SOCIAL FACEBOOK, TWITTER,

ANYTHING, WE CAN COMBINE THE

DATA SO WE CAN OVERLAY FOR

EXAMPLE, THE PATENT OFFICE AND

ALL LEGAL KEY FILINGS WITH THE

KEY PUD MED EXAMPLE AND EX--PUB

MED EXAMPLE AND EXTRACT GREATER

QUALITY OF RESULTS TO THAT.

SO WE'RE EXPANDING THE PLATFORM

TO INCLUDE MORE DATA AS YOU KNOW

PEOPLE SAY WE'RE INTEREST INDEED

THIS REPOSITORY OR THAT

REPOSITORY, AND WE HAVE ACCESS

TO THAT DATA, IT'S SIMPLE.

YOU SUPPLY THE DATA, THE

PLATFORM IS BUILT AND WE ADD IT

IN THERE AND CREATE NEW

PARAMETERS FOR IT AND KNOWLEDGE

BECOMES THAT MUCH GREATER IN

SCOPE.

>> NLM+ HAS BEEN FOCUSING ON

BIOMEDICAL KNOWLEDGE BASIS BUT

WE SEE A GREAT OPPORTUNITY IN

ENERGY WITH PARTICULAR EMPCISE

ON GREEN ENERGY AND A LOT OF WEB

APPLICATIONS SO WE'RE TRYING TO

DEVELOP SOME KNOWLEDGE BASES

THAT ARE MORE GENERAL BASED ON

THE WEB TO BE ABLE TO ADDRESS

THESE ISSUES.

>> LIKE EVERYBODY ELSE,

QUERTLE HAS A LOT OF WORK TO DO,

ADD VIDEO AND CONTENT SO ONE CAN

DO A SINGLE SEARCH ON ONE SITE

AND HIT AS MANY RELEVANT

DATABASES OF LITERATURE AS

POSSIBLE.

OUR BIG ACTIVITY RIGHT NOW IS

REWRITING SOME OF THE UNDERLYING

COMPONENTS SO IT'S VERY EASY TO

DEPLOY IN OTHER PEOPLE'S

SYSTEMS, AS WE HAVE FOUND A

NUMBER OF PEOPLE COMING TO US

ASKING CAN WE DEPLOY THESE

TECHNOLOGIES IN OUR PARTICULAR

SYSTEMS.

SO THAT'S OUR NUMBER ONE GOAL

RIGHT NOW.

>> GREAT.

>> ADAM DID YOU?

>> DON?

>> [INDISCERNIBLE], WHAT'S THE

BEST WAY TO GET YOUNGSTERS

INTERESTED IN CREATIVE VIEWS OF

THOSE.

>> IN CASE ANYONE DIDN'T HEAR

THAT, IT'S THE BEST WAY TO THEM

INTERESTED IN COMPUTERS.

>> THANK YOU FORU

DR. LINDBERGH, ONE OF THE THINGS

THAT THAT WE ARE DO SUGGEST I

GET TO GO TO MY MY SON'S SCHOOL

AND SCRATCH, SCRATCH IS A PREE

PROGRAM FROM M. I.T. FROM THE

LIFE LONG KINDERGARTEN GROUP AND

AND IT'S A PROGRAM AND LEGO

BLOCKS AND THEY PULL OVER THE

COATING BLOCKS TO ANIMATE

CHARACTERS, THEY CAN EVEN MAKE A

GAME IF THEY WANT OR MAKE A

STORY, SO IT'S GREAT FOR GIRLS

AND BOYS, THEY FOUND GIRLS

RESPOND MORE TO STORY TELLING

AND FOR A LITTLE BIT OLDER KIDS

ALICE IS A GREAT RESOURCE,

THAT'S A FREE PROGRAM FROM

CARNEGIE MELVIN DEVELOPED BY

RANDY POUSCH.

AND THERE THEY DID STUDIES WITH

GIRLS AND STORY TELLING AND THEY

GOT THEM TO PLAY FOR QUITE A

LONG TIME WHEN THEY USED THAT

APPROACH.

ONE OF THE THINGS WE FOLKSUS ON

WAS THE VISUAL ELEMENT, THE

CREATIVE VISUAL ELEMENT OF IT,

ONE OF OUR MAIN FOCUSES WAS ON

THIS--DISCOVERY EXPLORATION OF

OF INFORMATION AND YOU KNOW

COMING UP WITH THESE

SERENDIPITYS, THESEATISM ANNIES

OF SEEING THINGS YOU COULDN'T

SEE BEFORE--AND I THINK WITH
YOUNG

PEOPLE, THE CONCEPT OR DISCOVERY

OF EXPLORATION THAT HAVING THESE

THAT FASCINATE THEM AND WE

REALLY TRY TO CONNECT KNOWLEDGE

TO AN ARTISTIC JOURNAL

SCHEINTELLECTUAL JOURNAL SCHEI

THINK THAT'S ALSO SOMETHING THAT

YOUNG PEOPLE CAN VERY MUCH

CONNECT TO.

>> YES?

>> AS A UNIVERSAL DEVELOPER OF

DATA SETS AND APIs, I WOULD

LIKE TO ASK ALL THE PRESENTERS

WHAT CAN NLM DO TO MAKE YOUR

LIFE SIMPLER OR MORE

OPPORTUNITIES FOR DEVELOPING

APPs, SO IS IT ADDITIONAL DATA

SETS OR WAYS OF PRESENTING THE

DATA SETS.

>> I GUESS WE'RE SOFT, ALL THE

RESOURCES ARE AVAILABLE ARE

TREMENDOUS HELP AND I WOULD LIKE

TO SAY THAT PROBABLY THE BEST

THAT WE CAN GET IS ACTUALLY

ADVERTISEMENT OF EVERYTHING THAT

EXISTS BECAUSE WE MYSELF WE'RE

GOING THROUGH THE FTP DATA, I

WAS AMAZED AT EVERYTHING THAT I

DIDN'T KNOW EXIST.

>> THANK YOU FOR THAT QUESTION.

I WOULD LOOK TO SEE MORE IMAGES,

I WOULD LOVE TO SEE THAT WHEN

YOU DONATE YOUR BODY TO SCIENCE,

YOU DONATE YOUR IMAGES TO

SCIENCE AND THAT WE HAVE A VAST

STORE OF ANONYMIZED IMAGES FOR

PEOPLE TO USE.

>> I HAVE BEEN EXTREMELY

IMPRESSED WITH THE OPEN DATA

INITIATIVE WITH HOW RECEPTIVE

NLM HAS BEEN TO, YOU KNOW ALL MY

REQUESTS AND QUESTIONS AND YOU

KNOW, I THINK THAT AS FAR AS

RECEIVING DATA, IT'S BEEN

FANTASTIC.

NOW, MY HOPE IS THAT, YOU KNOW

WE CAN WORK WITH NLM TO HELP YOU

KNOW REACH A WIDER AUDIENCE FOR

WHAT WE DEVELOPED AND FIND, YOU

KNOW THE AREAS OF SYNERGY THAT

HELP US AND HELP NLM AND DO

GOOD.

>> I HAVE BEEN WORKING WITH AN

MLS DATABASE FOR QUITE A WHILE

AND IT'S A WONDERFUL RESOURCE,

BUT WHEN DOING

[INDISCERNIBLE]--I FOUND

MISSPELLING AND I WOULD LIKE TO

HAVE A WAY OF GIVING FEEDBACK SO

THAT WE CAN IMPROVE THE

DATABASE.

>> WE HAVE A FEATURE WHICH

WITHIN THE UMLS, THOSE OF YOU

WHO DON'T WORK FOR THIS,

ESSENTIALLY WE'RE ASSEMBLING

DATA WHICH IS PRODUCED BY OTHER

PEOPLE INTO THE MEDICAL SOURCE

AND WE DON'T EDSIT THEIR DATA

BECAUSE IT'S THEIR DATA BUT, WE

DO ADD LITTLE TAGS TO THINGS, WE

SORT OF SAY, HEY THIS IS A

SUPPRESSIBLE SYNONYM, FOR MOST

PEOPLE THIS WILL CAUSE YOU

PROBLEMS RATHER THAN HELP YOU.

SO THIS KIND OF FEEDBACK IS VERY

HELPFUL TO US.

>> I'D JUST LIKE TO ECHO ONE OF

THE FIRST COMMENTS WHICH IS AS

MUCH AS WE HAVE BEEN WORKING

WITH NLM DATA FOR QUITE A WHILE,

THERE'S STILL SURPRISES OF

WHAT'S THERE AND HAVING A BETTER

DESCRIPTION OF WHAT'S AVAILABLE

AND ALL THE PLACES YOU CAN FIND

IT, THERE'S FILES HIDDEN ON THE

FTP SITE THAT ARE NOT WELL

DESCRIBED THAT HAVE AMAZING

CAPABILITIES.

BUT ABSOLUTELY, THERE'S MORE TOO

BE DONE AND WE REALLY WANT TO

FIND WAYS TO TAKE ADVANTAGE OF

THAT AND PARTNER WITH NLM TO

MAKE THESE CAPABILITIES MORE

BROADLY AVAILABLE.

>> SO I THINK THAT WE HAVE COME

TO THE END OF OUR OFFICIAL TIME

HERE.

SO, I--BEFORE I SAY GOODBYE OR

CLOSING REMARKS, I WANT TO

REMIND EVERYONE THAT THESE

PEOPLE HAVE THEIR APPLICATIONS

SET UP OUTSIDE.

SO ANYBODY WHO WANTS TO GO AND

TAKE A LOOK AFTER THIS, I THINK

THEY'LL BE ABLE TO DO THAT WHICH

IS GREAT.

I WANT TO THANK EVERYONE FOR

COMING, I WANT TO THANK

ONE--THANK AGAIN DISCIPLINARY AB

BABSCY AND TREMENDOUS AMOUNT OF

WORK, XREAMLY WELL

DONE--EXTREMELY WELL DONE AND

THANK YOU FOR ANEESH AND TODD,

THANK YOU FOR COMING OUT HERE

BUT MOST IMPORTANTLY, THANK YOU

FOR SUBMITTING YOUR

APPLICATIONS.

THE AND IT WOULD HAVE BEEN

TERRIBLE TO HAVE A PARTY AND

HAVE NO ONE COME AND WE ARE

IMPRESSED AND DELIGHTED WITH THE

TREMENDOUS USE YOU'RE MAKING OF

OUR DATA.

THANK YOU VERY MUCH.

[ APPLAUSE ]