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The Genetic Basis of Kidney Cancer: Targeting the Metabolic Basis of Disease

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Air date: Wednesday, November 20, 2013, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 527 (116 Live, 411 On-demand)
Category: WALS - Wednesday Afternoon Lectures
Runtime: 01:05:55
Description: NIH Wednesday Afternoon Lecture

Annual Astute Clinican Lecture

Dr. Linehan has had a long-standing interest in identification of the genetic basis of cancer of the kidney. Kidney cancer is not a single disease. It is made up of a number of different types of cancer, each of which has a different histology, a different clinical course, which respond differently to therapy and are caused by different genes. Studies of the kidney cancer gene pathways have revealed that kidney cancer is fundamentally a metabolic disease. These findings have provided the foundation for the development of targeted therapeutic approaches for patients with advanced forms of this disease.

The annual Astute Clinician lecture within the NIH Director's Wednesday Afternoon Lecture Series (WALS) highlights exciting clinical observations that have served as a focus for research. This series has been made possible through the generous gift of the late Dr. Robert W. Miller, Scientist Emeritus, National Cancer Institute and his wife, Haruko (Holly) Miller.

For more information go to http://wals.od.nih.gov/
NLM Title: The genetic basis of kidney cancer : targeting the metabolic basis of disease / Dr. Marston Linehan.
Author: Linehan, Marston.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): NIH Wednesday Afternoon Lecture Annual Astute Clinican Lecture Dr. Linehan has had a long-standing interest in identification of the genetic basis of cancer of the kidney. Kidney cancer is not a single disease. It is made up of a number of different types of cancer, each of which has a different histology, a different clinical course, which respond differently to therapy and are caused by different genes. Studies of the kidney cancer gene pathways have revealed that kidney cancer is fundamentally a metabolic disease. These findings have provided the foundation for the development of targeted therapeutic approaches for patients with advanced forms of this disease.
Subjects: Carcinoma, Renal Cell--genetics
Carcinoma, Renal Cell--therapy
Kidney Neoplasms--genetics
Kidney Neoplasms--metabolism
Kidney Neoplasms--therapy
Publication Types: Lecture
Webcast
 
NLM Classification: WJ 358
NLM ID: 101622766
CIT Live ID: 13352
Permanent link: https://videocast.nih.gov/watch=13352

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