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My research program investigates how animals co-exist with microorganisms in the spectrum of interactions from mutualism to pathogenesis. We use the model vertebrate, zebrafish, to study the microbial communities of the intestine and ask how these communities influence the development and function of the host. We strive to understand how these systems of host-associated microbial communities assemble, how they function dynamically, and how they evolve. Our work employs genetic manipulations of host and bacteria, gnotobiology, live imaging, and ecological modeling to understand host-microbe interactions at many levels, ranging from molecules to populations.
The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.