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Solubility and Permeability Enhancement by New Nano-Micellar Natural Compounds

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Air date: Wednesday, July 14, 2010, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
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Category: OCCAM Lectures
Runtime: 01:09:24
Description: The NCI's Office of Cancer Complementary and Alternative Medicine (OCCAM) invites you to view its monthly lecture series.

With the goal of informing the National Cancer Institute (NCI) community about the variety of ongoing research in cancer and complementary and alternative medicine (CAM), NCI's Office of Cancer Complementary and Alternative Medicine (OCCAM) has created a monthly lecture series on cancer CAM. These hour long lectures, occurring from 10 a.m. - 11 a.m. on the second Wednesday of each month, will feature a fifty minute presentation on a cancer CAM topic and allow ten minutes for questions.

For more information, visit
http://www.cancer.gov/cam/news_lectures.html
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NLM Title: Solubility and permeability enhancement by new nano-micellar natural compounds [electronic resource] / Zhijun Liu ; NCI's Office of Cancer Complementary and Alternative Medicine (OCCAM).
Author: Liu, Zhijun.
National Cancer Institute (U.S.). Office of Cancer Complementary and Alternative Medicine.
Publisher:
Abstract: (CIT): In the research identifying bioactive natural compounds, a critical discovery was made that a natural compound rubusoside (RUB) has solubilizing properties. General applicability was shown over a wide spectrum of pharmaceutical compounds including paclitaxel, vitamin D3, progesterone, propofol, cyclosporine, etoposide, Co-Q10, roxithromycin, curcumin, quercetin, resveratrol, genistein, and others with enhancement ranging from 2- to over one million-fold. The underlying mechanisms of solubility-enablement, cell uptake and transport mechanisms, and toxicology of RUB remain new knowledge to gain.
Subjects: Antineoplastic Agents--administration & dosage
Glycosides
Micelles
Nanocapsules--administration & dosage
Solubility
Publication Types: Lectures
Webcasts
Download: To download this event, select one of the available bitrates:
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NLM Classification: QV 269
NLM ID: 101539609
CIT Live ID: 9381
Permanent link: http://videocast.nih.gov/launch.asp?16057