NIH VideoCast - Plasmacytoid Dendritic Cells Sense Nucleic Acid in Viral Infection and Autoimmune Disease

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Plasmacytoid Dendritic Cells Sense Nucleic Acid in Viral Infection and Autoimmune Disease

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Air date:	Wednesday, June 30, 2010, 4:15:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 239 * This only includes stats from October 2011 and forward.
Category:	Immunology
Runtime:	00:58:03
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Yong-Jun Liu is one of the best immunologists in the world. He has made significant contributions to several fields of immunology, especially human immunology. In his early work, he identified BCR and CD40 signaling as one of the major molecular mechanisms for selecting high affinity antigen specific B cells in germinal centers, an important mechanism for affinity maturation in antibody responses. He characterized human B cell subsets and identified molecular regulation of germinal center B cell differentiation. Yong-Jun is the one who discovered a new cell type in the immune system: plasmacytoid dendritic cells, which opened a new arena for dendritic cell immunology. Recently, he discovered a critical role for TSLP in DC-mediated allergic inflammation and T cell development. He has also shown that Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in the human thymus. Yong-Jun has published more than 200 papers which have been cited over 24,000 times. He has received many awards and honors for his outstanding work in immunology, including in 2006 The Dana Foundation Award for human Immunology Research and in 2007 The AAI Presidential Symposium Lecture. Yong-Jun is an engaging speaker who keeps his audience awake and on their toes and will undoubtedly deliver a seminar that you will not want to miss. The Immunology Interest Group

Author:	Dr. Yang-Jun Liu
CIT Live ID:	8693
Permanent link:	https://videocast.nih.gov/watch=8693

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