Control of the Cytoskeleton During Neurite Initiation and Axon Guidance

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Air date:	Monday, March 22, 2010, 12:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 180 * This only includes stats from October 2011 and forward.
Category:	Neuroscience
Runtime:	01:00:04
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Description:	Dr. Gertler has made fundamental contributions to our understanding of the relationship of signal transduction to cell motility, particularly in axon growth and guidance. He identified the founding member of the ENA/VASP family of proteins, encoded by the Drosophila gene enabled, as well as its mouse ortholog, MENA, and he has been a pioneer in uncovering the central role these proteins play in control of actin organization and dynamics. This work has been instrumental in shaping our view of how cell morphology and motility arises from the complex dynamics of the actin cytoskeleton. NIH Neuroscience Seminar Series

NLM Title:	Control of the cytoskeleton during neurite initiation and axon guidance / Frank Gertler.
Author:	Gertler, Frank. National Institutes of Health (U.S.)
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Abstract:	(CIT): Dr. Gertler has made fundamental contributions to our understanding of the relationship of signal transduction to cell motility, particularly in axon growth and guidance. He identified the founding member of the ENA/VASP family of proteins, encoded by the Drosophila gene enabled, as well as its mouse ortholog, MENA, and he has been a pioneer in uncovering the central role these proteins play in control of actin organization and dynamics. This work has been instrumental in shaping our view of how cell morphology and motility arises from the complex dynamics of the actin cytoskeleton.
Subjects:	Actins--physiology Axons--physiology Cytoskeleton--physiology Nerve Growth Factors Nerve Regeneration Nervous System--growth & development
Publication Types:	Lecture Webcast
NLM Classification:	WL 102.5
NLM ID:	101528444
CIT Live ID:	8562
Permanent link:	https://videocast.nih.gov/watch=8562

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