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Control of the Cytoskeleton During Neurite Initiation and Axon Guidance

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Air date: Monday, March 22, 2010, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
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Category: Neuroscience
Runtime: 01:00:04
Description: Dr. Gertler has made fundamental contributions to our understanding of the relationship of signal transduction to cell motility, particularly in axon growth and guidance. He identified the founding member of the ENA/VASP family of proteins, encoded by the Drosophila gene enabled, as well as its mouse ortholog, MENA, and he has been a pioneer in uncovering the central role these proteins play in control of actin organization and dynamics. This work has been instrumental in shaping our view of how cell morphology and motility arises from the complex dynamics of the actin cytoskeleton.

NIH Neuroscience Seminar Series
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NLM Title: Control of the cytoskeleton during neurite initiation and axon guidance [electronic resource] / Frank Gertler.
Series: NIH neuroscience seminar series
Author: Gertler, Frank.
National Institutes of Health (U.S.)
Publisher:
Other Title(s): NIH neuroscience seminar series
Abstract: (CIT): Dr. Gertler has made fundamental contributions to our understanding of the relationship of signal transduction to cell motility, particularly in axon growth and guidance. He identified the founding member of the ENA/VASP family of proteins, encoded by the Drosophila gene enabled, as well as its mouse ortholog, MENA, and he has been a pioneer in uncovering the central role these proteins play in control of actin organization and dynamics. This work has been instrumental in shaping our view of how cell morphology and motility arises from the complex dynamics of the actin cytoskeleton.
Subjects: Actins--physiology
Axons--physiology
Cytoskeleton--physiology
Nerve Growth Factors
Nerve Regeneration
Nervous System--growth & development
Publication Types: Lectures
Webcasts
Download: To download this event, select one of the available bitrates:
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NLM Classification: WL 102.5
NLM ID: 101528444
CIT Live ID: 8562
Permanent link: http://videocast.nih.gov/launch.asp?15733

 

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