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Tuning Depression Circuits Using Deep Brain Stimulation

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Air date: Wednesday, February 17, 2010, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
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Category: WALS - Wednesday Afternoon Lectures
Runtime: 01:08:15
Description: Critical to development of deep brain stimulation (DBS) as a novel therapy for treatment resistant depression has been the evolving characterization of brain systems mediating normal and abnormal mood states as well as those mediating successful and unsuccessful response to various antidepressant interventions. Building on converging functional neuroimaging evidence implicating the subcallosal cingulate as a critical node within this depression network, we targeted this region adapting neuromodulation techniques routinely used to treat Parkinson’s disease and other movement disorders. The theoretical and data-driven foundation for piloting this new procedure as well as long-term clinical and imaging findings from ongoing experimental studies will be presented.

The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
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NLM Title: Tuning depression circuits using deep brain stimulation [electronic resource] / Helen Mayberg.
Series: NIH Wednesday afternoon lecture series
Author: Mayberg, Helen S.
National Institute of Mental Health (U.S.)
Publisher:
Other Title(s): NIH Wednesday afternoon lecture series
Abstract: (CIT): Critical to development of deep brain stimulation (DBS) as a novel therapy for treatment resistant depression has been the evolving characterization of brain systems mediating normal and abnormal mood states as well as those mediating successful and unsuccessful response to various antidepressant interventions. Building on converging functional neuroimaging evidence implicating the subcallosal cingulate as a critical node within this depression network, we targeted this region adapting neuromodulation techniques routinely used to treat Parkinson"s disease and other movement disorders. The theoretical and data-driven foundation for piloting this new procedure as well as long-term clinical and imaging findings from ongoing experimental studies will be presented. The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Subjects: Deep Brain Stimulation--methods
Depressive Disorder--therapy
Publication Types: Lectures
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NLM Classification: WM 171
NLM ID: 101525643
CIT Live ID: 8236
Permanent link: http://videocast.nih.gov/launch.asp?15724

 

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