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Gridlock on the Genomic Beltway: How Epigenetic Gene Silencing Shapes our Cellular Phenotypes

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Air date: Wednesday, October 14, 2009, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
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Category: WALS - Wednesday Afternoon Lectures
Runtime: 00:58:26
Description: Dr. Rauscher's research at Wistar focuses on the molecular genetics of cancer. In particular, he is interested in the structure-function aspects of tumor suppressor and oncogene proteins, mechanisms of transcriptional regulation, transcriptional control of cellular differentiation programs and organogenesis.

Several years ago, he and his research team described the function of the WT1 gene that, when mutated, causes Wilms' Tumor. More recently, Dr. Rauscher and his team discovered BAP1, a gene encoding an enzyme that helps regulate levels of BRCA1 and is involved in the development of breast and lung cancers.

The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
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NLM Title: Gridlock on the genomic beltway : how epigenetic gene silencing shapes our cellular phenotypes [electronic resource] / Frank J. Rauscher III.
Series: NIH director's Wednesday afternoon lecture series
Author: Rauscher, F J.
National Institutes of Health (U.S.)
Publisher:
Other Title(s): NIH director's Wednesday afternoon lecture series
Subjects: Cell Differentiation--physiology
Gene Silencing--physiology
Genome, Human--genetics
Phenotype
Publication Types: Lectures
Webcasts
Download: To download this event, select one of the available bitrates:
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NLM Classification: QU 475
NLM ID: 101518972
CIT Live ID: 7897
Permanent link: http://videocast.nih.gov/launch.asp?15355

 

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