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In last few centuries subpopulations of dogs have developed into closed populations as a result of differential selection for traits associated with both behavior and appearance. This practice, coupled with small numbers of founders for many breeds has generated a population that is ideal for mapping genes underlying morphology, behavior, and disease susceptibility. In today's lecture we will summarize advances regarding the canine genome project and current approaches for finding genes controlling both simple and complex traits. In particular, we will discuss genes controlling body size, fur texture, and leg length, and the implications of these findings for advancing our knowledge regarding disease gene mapping.
Genetics and the shapes of dogs [electronic resource] / Elaine Ostrander.
Series:
Dog genes tell surprising tales : finding genes for complex traits
Author:
Ostrander, Elaine A. National Institutes of Health (U.S.)
Publisher:
[Bethesda, Md. : National Institutes of Health, 2008]
Other Title(s):
Dog genes tell surprising tales : finding genes for complex traits
Abstract:
(CIT): In last few centuries subpopulations of dogs have developed into closed populations as a result of differential selection for traits associated with both behavior and appearance. This practice, coupled with small numbers of founders for many breeds has generated a population that is ideal for mapping genes underlying morphology, behavior, and disease susceptibility. In today's lecture we will summarize advances regarding the canine genome project and current approaches for finding genes controlling both simple and complex traits. In particular, we will discuss genes controlling body size, fur texture, and leg length, and the implications of these findings for advancing our knowledge regarding disease gene mapping.
Subjects:
Athletic Performance Body Size--genetics Chromosome Mapping Dogs--genetics Hair
