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Dr. Sklar, a neuroscientist, human geneticist and clinical psychiatrist, is an investigator in search for the genetic causes of psychiatric disorders, including schizophrenia, bipolar disorder, autism, and ADHD. A major focus of her lab is to develop tools for understanding and characterizing human genetic sequence variation and to select candidate genes for study based on evidence obtained from family-based linkage analysis, expression arrays, and biological data. Recent contributions are to the understanding of gene variants and structural variants that influence the risk of bipolar disorder and autism. Dr. Sklar is a founding member of the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard and serves as director of genetics. She is also part of a large consortium of researchers across the country collecting patient samples in collaboration with the STEP-BD program for the largest-ever association study in bipolar disorder.
