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Air date:
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Wednesday, March 29, 2006,
3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
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Category:
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Wednesday Afternoon Lectures
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Sharing:
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Description:
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The human genome project has provided two significant challenges. First, how to identify sites of variation in the human genome which make significant contributions to human disease. Second, as these sites of variation are identified, to develop effective intervention strategies based on this knowledge to improve human health. I will discuss two specific lines of research which relate to these challenges. I will discuss our efforts to move from the identification of the Huntington's Disease gene towards the identification of small molecules which can ameliorate or block its pathological effects. I will then discuss strategies for the identification of genes for complex human genetic traits focused on the ways in which genome-wide SNP and haplotype analysis can achieve maximum power.
http://web.mit.edu/biology/www/facultyareas/facresearch/housman.shtml
WALS
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Runtime:
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01:13:27
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NLM Title:
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Huntington's and haplotypes : meeting the challenges of the genome [electronic resource] / David E. Housman.
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Series:
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Wednesday afternoon lecture
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Author:
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Housman, David E.
National Institutes of Health (U.S.)
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Publisher:
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[Bethesda, Md. : National Institutes of Health, 2006]
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Other Title(s):
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Wednesday afternoon lecture
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Subjects:
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Genetic Research
Haplotypes
Huntington Disease--genetics
Huntington Disease--physiopathology
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Publication Types:
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Government Publications
Lectures
Webcasts
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Download:
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Download Video
How to download a Videocast
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NLM Classification:
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WL 390
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NLM ID:
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101289625
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CIT File ID:
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13135
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CIT Live ID:
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4283
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Permanent link:
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http://videocast.nih.gov/launch.asp?13135
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