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How DNA Viruses Deal with Stress

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Air date: Wednesday, November 16, 2005, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
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Category: Wednesday Afternoon Lectures
Runtime: 01:12:20
Description: Today’s talk examines how DNA viral infections deal with the consequences of inducing cellular stress responses. During infection by human cytomegalovirus (HCMV) and simian virus 40 (SV40), cellular stress responses are triggered due to the stress of the viral infection, for example, the greatly increased metabolic and synthetic rates needed to produce new virions. The stress responses may be induced due to nutrient deprivation, hypoxia or the induction of the unfolded protein response (UPR), a form of endoplasmic reticulum stress.

For more information, visit
http://www.med.upenn.edu/camb/faculty/mv/alwine.html

The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
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Author: Jim Alwine, Ph.D., University of Pennsylvania
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CIT Live ID: 4252
Permanent link: http://videocast.nih.gov/launch.asp?12906