NIH VideoCast - Molecular of Biology of Mammalian Prions Seminar

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Molecular of Biology of Mammalian Prions Seminar

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Air date:	Tuesday, January 27, 2004, 10:00:00 AM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 148 * This only includes stats from October 2011 and forward.
Category:	Special
Runtime:	00:55:14
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	Prions have been responsible for an entire century of tragic episodes. Fifty years ago, Kuru decimated the population of Papua New Guinea. Then, iatrogenic transmission of prions caused more than 250 cases of Creutzfeldt-Jakob disease. More recently, transmission of bovine spongiform encephalopathy to humans caused a widespread health scare. On the other hand, the biology of prions represents a fascinating and poorly understood phenomenon, which may account for more than just diseases, and may represent a fundamental mechanism of cross-talk between proteins. The two decades since Stanley Prusiner's formulation of the protein-only hypothesis have witnessed spectacular advances, and yet some of the most basic questions in prion science have remained unanswered.

NLM Title:	Molecular biology of mammalian prions seminar / Adriano Aguzzi.
Author:	Aguzzi, Adriano. National Institutes of Health (U.S.)
Publisher:
Abstract:	(CIT): Prions have been responsible for an entire century of tragic episodes. Fifty years ago, Kuru decimated the population of Papua New Guinea. Then, iatrogenic transmission of prions caused more than 250 cases of Creutzfeldt-Jakob disease. More recently, transmission of bovine spongiform encephalopathy to humans caused a widespread health scare. On the other hand, the biology of prions represents a fascinating and poorly understood phenomenon, which may account for more than just diseases, and may represent a fundamental mechanism of cross-talk between proteins. The two decades since Stanley Prusiner's formulation of the protein-only hypothesis have witnessed spectacular advances, and yet some of the most basic questions in prion science have remained unanswered.
Subjects:	Gene Expression Mammals Prion Diseases Prions
Publication Types:	Lecture Webcast
Rights:	This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
NLM Classification:	QU 55
NLM ID:	101268349
CIT Live ID:	3057
Permanent link:	https://videocast.nih.gov/watch=3057

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