Functional Proteomics: Methods Development and Applications to Signal Transduction

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Air date:	Wednesday, December 10, 2003, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 95 * This only includes stats from October 2011 and forward.
Category:	WALS - Wednesday Afternoon Lectures
Runtime:	01:08:32
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Description:	Functional proteomics provides a powerful approach to screen for molecular responses at the protein level. By combining 2D gels and mass spectrometry with standard molecular pharmacological strategies, responses to specific signal transduction pathways can be monitored. The results reveal novel targets for regulation by post-translational modification, which compliment information from gene array analyses. Applications to MAP kinase and Rho GTPase pathways will be presented. 2D-gel based approaches also reveal proteins that are differentially expressed between melanocyte vs melanoma cultured cell lines. For more information, visit Natalie Ahn NIH Director's Wednesday Afternoon Lecture Series.

Author:	Natalie G. Ahn, Ph.D., University of Colorado
Rights:	This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
CIT Live ID:	2592
Permanent link:	https://videocast.nih.gov/watch=2592

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